Artificial Intelligence
Lord Global Corporation (n/k/a 27 Health Holdings Corp.) Shareholder Update September 14th 2020
CHICAGO, Sept. 14, 2020 (GLOBE NEWSWIRE) — As CEO of Lord Global corporation, I’d like to clarify the history of the Company. While we await FINRA approval to officially be 27 Health Holdings Corp., we are still known as Lord Global Corporation in the stock market. Our symbol will remain (LRDG) even after the name change is approved. In January, we invested into a publicly traded company named Bigfoot Projects Inc.(OTC:BGFT). Simultaneously with this investment, we took control of the Board of Directors and sold 81% of the prior company’s business to the company’s former CEO, Tom Biscardi. The company has no operational connection nor any association with the former CEO or any of its former board members. The Company made a decision to operate out of its wholly-owned subsidiary, 27Health Inc. All of our focus and subsequent capital raises have been to further the mission of 27Health Inc. that we revealed in our prior shareholder letter dated June 5th 2020. Alexandra Aizenshtadt and I are presently the only members of the Board of Directors. However, we intend to augment the board with individuals who have the relevant expertise we need to further 27Health Inc.’s businesses. I would now like to update you on the Company’s progress since our last shareholder update.
The Company announced on July 7th 2020 a joint venture with J.A. Lafayette Consulting. J.A. Lafayette is a minority, Black-owned operation focusing on financing and supporting established Black-owned businesses. There are an estimated over 2 million Black business establishments in the U.S. J.A. Lafayette, with our access to capital, is concentrating on helping these businesses connect to capital markets in order to accelerate their growth. As a result of this relationship, we’ve signed a collaborative agreement with Innovative Regulatory Risk Advisors LLC. (IRRA). IRRA is an SBA8(a) licensee which allows them to sell any product to the U.S. federal government on a no bid basis. We have established a mentor/protégé relationship with IRRA under this SBA program. On August 10th, the Company announced that, in collaboration with IRRA and others, we signed our first major fuel supply contract to deliver fuel to a series of distributors, that would generate the Company in excess of $50 million of revenue per week. This revenue would generate a significant operating margin to The Company once we secured a fuel reseller agreement. Last week on September 10th, we announced that IRRA and 81 Logistics Group LLC. had signed an agreement with ExxonMobil to be a reseller of all types of fuel. The Company has established an administrative and financing agreement with 81 Logistics Group LLC. and its founder, NFL Hall of Famer, Tim Brown. 81 Logistics Group LLC. is one of the few Black-owned companies that can distribute fuel in all 50 states. This will enable the Company to deliver on the prior $50 million per week fuel contract. In addition, this reseller agreement will enable IRRA to pursue contracts which the U.S. Federal Government offers to such SBA8(a) licensees. We believe that there are few if any Black-owned SBA8(a) licensees able to sell fuel to the Federal Government. In addition, we believe we are unique among public companies to have this opportunity. The Federal government buys an inordinate amount of fuel on a monthly basis. We are confident that our agreements with IRRA and 81 Logistics Group LLC. will generate significant excess cash flow to the company on a monthly basis. We intend to utilize our agreements with IRRA and 81 Logistics Group LLC. to cross-sell our healthcare products which are designed to benefit from the structural changes in our society due to the pandemic to both the Federal Government as well as the Black business community. We are extremely excited about working with Tim Brown and IRRA in this regard.
On September 10th the Company also announced an administrative and financing agreement with KeyOptions Inc. an Australian data analysis and implementation company. KeyOptions has the master distribution rights to distribute the Virolens® product to the following regions: Asia, Australia, New Zealand and other Oceania countries. The highly scalable Virolens® COVID-19 screening The Virolens®️ system is a COVID-19 screening device based on microscopic holographic imaging and artificial intelligence (AI) software technology. It uses a digital camera attached to a microscope to analyze saliva samples, with the data run through a computer which is trained to identify the virus from other cells, delivering an end result in just 20 seconds. The Virolens® system was trained to recognize the COVID-19 virus particles in saliva using a range of samples of COVID-19 virus provided by virologists working on the virus at the University of Bristol. The Virolens®️ system has a 99.8% sensitivity and 96.7% specificity, based on the results of an internal in-vitro validation study, demonstrating an exciting proof of concept. The administrative and financing agreement between KeyOptions Inc. and our Company enables 27 Health Holdings Corp. to report all the revenue generated by this product in the markets that KeyOptions is licensed in, while allowing KeyOptions to remain private. The Company’s relationship is to help administer and finance KeyOption’s Virolens® business. KeyOptions is receiving, based on milestones, a convertible preferred in our stock that will convert into between 1.5 to 3 million common shares.
We are extremely proud to have successfully completed these two administrative and financing agreements, both of which we expect could generate substantial revenue to the Company. Our unique administrative and financing agreements are a structure that enables our public company to successfully engage with companies that would prefer to stay private, while allowing them the opportunity to access public capital by virtue of being shareholders of our company. We intend to utilize this technique in future such endeavors.
We would also like to update the shareholders on the progress Coviguard Inc. has made in the production of the Oral Sanitizer, Coviguard™. Coviguard Inc. has selected two outsourced manufacturers. They have received enough ingredients to complete sample batches, and we have been told that we will be receiving those samples shortly. It has taken longer than anticipated due to each manufacturer’s dealings with its own pandemic slowdown. However, Coviguard Inc. believes that we are very close to getting our first production run and we look forward to fulfilling Global Cannabinoid’s subsidiary, Global Sanitizer’s pending order.
In response to the SEC, the Company filed an 8k detailing its response to the SEC’s suspension of trading from August 20th to September 4th. We feel that we have appropriately disclosed everything in relation to the Coviguard™ product and are pleased that trading has resumed. The Company intends to file a 15c-211 with a broker/dealer as soon as possible. In the meantime, we are trading on the Expert Market which enables any investor to use any electronic trading platform to buy and sell shares.
While this past month has brought unexpected challenges, we at 27 Health Holdings Corp. are proud that we have come out of this in an even stronger position than before. In combination with our new strategic partners, we are confident that together we will increase shareholder value.
Joseph Frontiere
CEO of Lord Global Corporation
(n/k/a 27 Health Holdings Corp.)
About Lord Global Corporation
Lord Global Corporation intends to focus on the business development of its 27Health Inc. subsidiary. 27Health Inc. is dedicated to financing and marketing innovative, healthcare related products that are and will benefit from the permanent changes caused by the recent pandemic. It is our feeling that this crisis has accelerated the market share of direct to consumer healthcare products and services. Prior to the crisis, the direct to consumer cloud-based market was among the fastest growing, subsequent to this crisis, we believe that 10 years’ worth of market share has been condensed into several months. Hence, we have signed collaboration and distribution agreements with several companies. We believe that focusing on independent contractors and GIG-economy workers for all these products and services will help us in cross-selling each of these products and services to the same database. The Independent contractor and GIG-economy worker has been and is the fastest growing component of the U.S. labor supply and is estimated to be at least 60 million people. We are also laser focusing on a significant subset of this group, the Black business community through our minority owned subsidiary J.A. Lafayette. The pandemic is teaching individuals forced to work from their home to become adept at telecommuting. We believe coming out of this crisis, a large number of these individuals will prefer to work from their phones and computers and from any location as opposed to a fixed office. This will hyper-accelerate the already significant growth of this component of the U.S. labor supply. We believe that marketing health related products and services to this market will make us one of the fastest growing healthcare marketing companies.
Safe Harbor Statement
This press release includes statements that may constitute forward-looking statements made pursuant to the safe harbor provision of the Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates,” and similar statements. Statements that are not historical facts, including statements about the Company’s beliefs and expectations, are forward-looking statements. Forward-looking statements involve inherent risks and uncertainties that could cause actual results to differ materially from the forward-looking statements. For example, statements about future revenues and the Company’s ability to fund its operations and contractual obligations are forward looking and subject to risks. Several important factors could cause actual results to differ materially from those contained in any forward-looking statement. Potential risks and uncertainties include, but are not limited to, the inability to raise capital to support the Company through its growth stage, the Company’s inability to generate projected sales and trade relations between the United States. The Company does not undertake any obligation to update any forward-looking statement, except as required under applicable law.
27Health, Inc. PR Contact Information
Sean Carter
[email protected]
Artificial Intelligence
Kanazawa University research: Biochemical tails tell a story
KANAZAWA, Japan, April 24, 2024 /PRNewswire/ — Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nano Letters how the use of high-speed atomic force microscopy helps to understand the crucial role played by certain biomolecules in DNA wrapping dynamics.
In plants and animals, the basic packaging units of DNA, which carry genetic information, are the so-called nucleosomes. A nucleosome consists of a segment of DNA wound around eight proteins known as histones. During gene expression (the process lying at the basis of protein production), nucleosomes are involved in various dynamical structural changes, such as nucleosome sliding, DNA unwrapping and other DNA–histone interactions. Of particular importance in these processes are the end structures, or tails, of the histones. Histone tails undergo chemical modifications, changing the histone’s functionality as needed. Detailed studies, and especially visualizations, of nucleosome dynamics are crucial for better understanding the role of histone tails. Mikihiro Shibata from Kanazawa University and colleagues have now succeeded in making video recordings of tail-less nucleosomes, showing that the absence of histone tails significantly increases a nucleosome’s dynamic activity.
The scientists used high-speed atomic force microscopy (HS-AFM), a powerful nanoimaging tool for visualizing molecular structures and their dynamics at high spatial and temporal resolution. For this, the nucleosomes needed to be put onto a substrate. Shibata and colleagues used a film of so-called pillar[5]arenes (molecules with a pentagonal tubular structure) as the substrate, forming an ideal surface as the nucleosomes are easily adsorbed to it without dynamical processes getting suppressed.
The researchers first looked at nucleosomes for which all eight histones lacked tails. Based on their HS-AFM observations, they concluded that nucleosome sliding and DNA unwrapping/rewrapping occurred more often than for normal (canonical) nucleosomes. This suggests that without tails, the histone–DNA interaction is weakened, leading to a situation in which DNA can more easily detach from the histones.
To better understand the roles of specific histone tails, Shibata and colleagues prepared nucleosomes where one type of histone was tailless. There are four different types of histones, called H2A, H2B, H3 and H4. HS-AFM experiments on the nucleosomes revealed that H2B and H3 tail-less nucleosomes showed an increased frequency of dynamics. Conversely, this means that canonical H2B and H3 histones are essential for nucleosome stability.
The scientists point out that they could not observe any actual motion of histone tails — most likely the temporal resolution of the study, 0.3 seconds, was much slower than the rate of the wrapping/unwrapping dynamics of the tails. Despite this limitation, the work of Shibata and colleagues clearly proves that the tails of H2B and H3 histones are the main contributors to nucleosome dynamics. Regarding future work, quoting the researchers, “a technique for tagging histone tail tips might enable HS-AFM to capture the movements of the histone tails themselves.”
Background
High-speed atomic force microscopy
The general principle of atomic force microscopy (AFM) is to make a very small tip scan the surface of a sample. During this horizontal (xy) scan, the tip, which is attached to a small cantilever, follows the sample’s vertical (z) profile, inducing a force on the cantilever that can be measured. The magnitude of the force at the xy position can be related to the z value; the xyz data generated during a scan then result in a height map providing structural information about the investigated sample. In high-speed-AFM (HS-AFM), the working principle is slightly more involved: the cantilever is made to oscillate near its resonance frequency. When the tip is moved around a surface, the variations in the amplitude (or the frequency) of the cantilever’s oscillation — resulting from the tip’s interaction with the sample’s surface — are recorded, as these provide a measure for the local z value. AFM does not involve lenses, so its resolution is not restricted by the so-called diffraction limit as in X-ray diffraction, for example.
HS-AFM results in a video, where the time interval between frames depends on the speed with which a single image can be generated (by xy-scanning the sample). Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have in recent years developed HS-AFM further, so that it can be applied to study biochemical molecules and biomolecular processes in real-time. Mikihiro Shibata and colleagues have now applied the method to study nucleosome dynamics in detail, and in particular the role of the molecular endings of histones — proteins that play a crucial role in DNA accessibility.
Reference
Shin Morioka, Takumi Oishi, Suguru Hatazawa, Takahiro Kakuta, Tomoki Ogoshi, Kenichi Umeda, Noriyuki Kodera, Hitoshi Kurumizaka, and Mikihiro Shibata. High-Speed Atomic Force Microscopy Reveals the Nucleosome Sliding and DNA Unwrapping/Wrapping Dynamics of Tail-less Nucleosomes, Nano Letters ,2024.
DOI: 10.1021/acs.nanolett.4c00801https://pubs.acs.org/doi/10.1021/acs.nanolett.4c00801
https://nanolsi.kanazawa-u.ac.jp/wp/wp-content/uploads/Figure-1-12.png Figure 1.
High-speed atomic force microscopy visualization of nucleosome dynamics with canonical (top) and tail-less (bottom) histones.© 2024 American Chemical Society
ContactHiroe YonedaSenior Specialist in Project Planning and OutreachNanoLSI Administration Office, Nano Life Science Institute (WPI-NanoLSI)Kanazawa UniversityKakuma-machi, Kanazawa 920-1192, JapanEmail: [email protected]: +81 (76) 234-4555
About Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Understanding nanoscale mechanisms of life phenomena by exploring “uncharted nano-realms”
Cells are the basic units of almost all life forms. We are developing nanoprobe technologies that allow direct imaging, analysis, and manipulation of the behavior and dynamics of important macromolecules in living organisms, such as proteins and nucleic acids, at the surface and interior of cells. We aim at acquiring a fundamental understanding of the various life phenomena at the nanoscale.https://nanolsi.kanazawa-u.ac.jp/en/
About the World Premier International Research Center Initiative (WPI)
The WPI program was launched in 2007 by Japan’s Ministry of Education, Culture, Sports, Science and Technology (MEXT) to foster globally visible research centers boasting the highest standards and outstanding research environments. Numbering more than a dozen and operating at institutions throughout the country, these centers are given a high degree of autonomy, allowing them to engage in innovative modes of management and research. The program is administered by the Japan Society for the Promotion of Science (JSPS).
See the latest research news from the centers at the WPI News Portal: https://www.eurekalert.org/newsportal/WPI
Main WPI program site: www.jsps.go.jp/english/e-toplevel
About Kanazawa University
As the leading comprehensive university on the Sea of Japan coast, Kanazawa University has contributed greatly to higher education and academic research in Japan since it was founded in 1949. The University has three colleges and 17 schools offering courses in subjects that include medicine, computer engineering, and humanities.
The University is located on the coast of the Sea of Japan in Kanazawa – a city rich in history and culture. The city of Kanazawa has a highly respected intellectual profile since the time of the fiefdom (1598-1867). Kanazawa University is divided into two main campuses: Kakuma and Takaramachi for its approximately 10,200 students including 600 from overseas.http://www.kanazawa-u.ac.jp/e/
View original content:https://www.prnewswire.co.uk/news-releases/kanazawa-university-research-biochemical-tails-tell-a-story-302125876.html
Artificial Intelligence
Geek+ and System Teknik deploy first PopPick solution in the Nordics for the pharmacy group Med24.dk
DUSSELDORF, Germany, April 24, 2024 /PRNewswire/ — Geekplus, the global leader in mobile robot and smart logistics solutions, has deployed the first Shelf-to-Person PopPick project in the Nordics for one of the biggest online pharmacy wholesalers in the region, Med24.dk. System Teknik partnered on the Denmark project, which includes three PopPick stations and 30 Shelf-to-Person robots, bringing a flexible solution to a region where fixed automation still dominates.
“With the rise of e-commerce, Med24.dk had been struggling with huge sales growth coupled with fast delivery demands from customers in Denmark, Norway, Sweden searching for pharmacy, health and beauty products. Peak season events had also caused considerable strain to their operations,” said Blond Shkodrani, channel partner manager for the Nordics at Geekplus. “Due to their overwhelming success, Med24.dk needed a modular, automated order fulfillment solution for fast, efficient order fulfillment.”
The Geekplus modular Shelf-to-Person solution optimizes warehouse operations using mobile robots to transport shelves. In a region where fixed and cubic solutions have been the trend during recent years, Shelf-to-Person handles goods of all sizes while removing the need for infrastructure investment, making it the most flexible response to order fulfillment challenges.
PopPick workstations use two retrieval arms and four presentation locations to present pickers with multiple, moveable 78-tote racks at one time, resulting in an industry-leading throughput of 450 totes per hour. PopPick can store goods of all types and sizes; the solution is not limited to small pieces and improves ergonomics for workers while picking. It also takes up less space than traditional systems, so customers can use more stations without adding facility space.
“We are very pleased to invest in flooring robots from Geekplus,” said Med24.dk CEO Nils Træholt. “We believe that this new and innovative technology can help us realize our growth ambitions, while maintaining good delivery times for the benefit of our customers.”
Morten Kirch, System Teknik’s CSO, added: “Due to Med24.dk’s growth, we are thrilled to be able to deliver a tailor-made, automated solution that matches their needs.”
Geekplus offers a suite of Goods-to-Person mobile order fulfillment solutions — the only comprehensive robotic offering controlled by a single software platform.
“Through trusted partners like System Teknik, we’re showing customers all over Europe that Geekplus truly is a one-stop shop for modular warehouse automation,” Shkodrani said.
Photo – https://mma.prnewswire.com/media/2395198/Med24_Geekplus_PopPick.jpg Logo – https://mma.prnewswire.com/media/2373458/Geekplus_logo.jpg
View original content:https://www.prnewswire.co.uk/news-releases/geek-and-system-teknik-deploy-first-poppick-solution-in-the-nordics-for-the-pharmacy-group-med24dk-302125816.html
Artificial Intelligence
VdoCipher’s Video Piracy Tracker Engine Blocks 60,000+ Pirates on 700+ Platforms
The company has global footprints across 120+ countries, serves over 10,000+ content creators, and educators across 3,000+ platforms
GURUGRAM, India, April 24, 2024 /PRNewswire/ — VdoCipher, a leading provider of video player and piracy protection solutions for content creators, e-learning, and media platforms, has announced significant success in combating video piracy with its latest innovation, the Piracy Tracker Engine. In just six months, this cutting-edge technology has blocked over 60,000 piracy attempts across 700+ content platforms, reinforcing VdoCipher’s commitment to safeguarding digital content and revenues.
For over eight years, VdoCipher has been pioneering DRM Encryption and Dynamic Watermark technologies, offering robust security solutions to content creators worldwide. Six months ago, the company introduced the Piracy Tracker and Hacker Identification Engine, aimed at identifying and blocking piracy attempts. This innovative solution targets various forms of piracy, including DRM breaches, credential sharing, and illegal clone applications.
VdoCipher, with a significant presence across the European market, serves over 10,000+ content creators across 3,000 platforms. Vibhav Sinha, CTO, VdoCipher, commented, “Every year we try to add an additional layer of technology to our security stack. Adding to strong Video DRM encryption, we now identify a combination of 12 viewer behavior patterns using our secure player. We provide an easy-to-use dashboard for our customers to get all piracy info. Some of the popular e-learning platforms have already made use of this tool to catch hackers, grow users, and enhance their revenues.”
The proliferation of internet video piracy tools poses a significant challenge, particularly in Europe. Recent statistics reveal that streaming accounted for 58% of piracy in the EU in 2022, with downloading comprising 32%. Top 10 popular global video downloaders have 110+ Million users.
Additionally, a report analyzing online piracy facts worldwide shows that Europeans have the biggest piracy problem (45.72%). In Italy, Spain, Portugal, Germany, UK and France, film piracy has soared during the Covid19 pandemic. Moreover, Telegram and other platforms have facilitated the widespread dissemination of pirated content, with hundreds of groups each having over 10,000 users leaking course videos.
In the past six months, VdoCipher’s Piracy Tracker Engine has yielded impressive results:
63,210 sessions blocked for potential piracy attempts.12,330 unique devices/IPs blocked.1,690 users were detected for credential misuse.384 user accounts proactively blocked based on piracy data.Legal actions were initiated against 5 users.Siddhant Jain, CEO of VdoCipher, emphasized, “One problem in online education and the content creator economy that no one talks about is video piracy. Video piracy robs creators of revenue but also robs students of learning from good-quality teachers. Teachers fear putting their best content online due to piracy; so ultimately, it also harms the student community. At VdoCipher, with our video hosting solutions, it is our mission to bring more educators and content creators online by ensuring that they do not lose revenues due to online piracy; at the same time, viewers across the globe have the best viewing experience.”
Contact: Siddhant [email protected]
Logo: https://mma.prnewswire.com/media/2394780/VdoCipher_Logo.jpg
View original content:https://www.prnewswire.co.uk/news-releases/vdociphers-video-piracy-tracker-engine-blocks-60-000-pirates-on-700-platforms-302124573.html
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