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Study Published in Nature Medicine Shows Positive Impact of Leveraging Federated Learning for Healthcare AI

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BOSTON, Sept. 15, 2021 (GLOBE NEWSWIRE) — Rhino Health today announced that the EXAM study (EMR CXR AI Model), led by its co-founder and CEO Ittai Dayan, MD, and Mona Flores, MD, global head of medical AI for NVIDIA, has been published in Nature Medicine. This is the world’s largest and most prominent study to-date utilizing federated learning (FL) to train a healthcare AI solution on diverse data across institutions. With FL, artificial intelligence models are trained using data from disparate sources — without sharing or aggregating data. This protects privacy, facilitates access to more diverse datasets, and makes it easier for AI researchers and developers around the world to collaborate.

“Federated learning promises to accelerate creation and adoption of AI-based healthcare solutions that work more effectively for more patients in more places,” said Dr. Flores. “EXAM demonstrates the positive impact of leveraging diverse and disparate datasets and underscores the potential for more widespread usage of the FL-based approach.” 

The EXAM study, conducted in Fall 2020, brought together 20 institutions across North and South America, Europe, and Asia to create an AI model that could accurately predict future oxygen requirements of an individual seen in the emergency department with COVID-19 symptoms. Inputs included vital signs, laboratory data, and chest x-rays. EXAM achieved an average area under the curve (AUC) of over 0.92, an average improvement of 16% and a 38% increase in generalizability over local models. The model remained robust to a gold-standard validation conducted at three separate, independent sites. This provided the broader healthcare community with a validated model to respond to COVID-19 challenges, as well as setting the stage for broader use of FL in healthcare. A full description and complete findings are available here.

“Federated learning is a promising tool that can accelerate the clinical translation of AI models by ensuring they retain a consistent level of performance across today’s real-world patient ecosystem,” said Christoph Wald, MD, PhD, MBA, FACR, who serves as Radiology Chair at Lahey Hospital and Medical Center and is Chair of the American College of Radiology (ACR) commission on informatics. “This large-scale study is the first to demonstrate the impact of federated learning on patient outcomes globally and provides a strong foundation for continued improvement and accelerated adoption of advanced AI solutions.” 

“Seeing firsthand the transformative power of federated learning made it clear to me that the health ecosystem needs to rethink how we manage data-sharing,” said Fiona Gilbert, MD, chair of Radiology at the University of Cambridge School of Medicine. “The ability to collaborate globally while always prioritizing and protecting privacy is essential to innovations in diagnostics and treatment pathways that will improve outcomes for today’s large and increasingly diverse patient populations.”

Currently, Rhino Health is collaborating with several partners including the Center for Advanced Medical Computing and Analysis (CAMCA), Massachusetts General Hospital (MGH), University of Cambridge School of Clinical Medicine, and several other prominent academic medical centers and research consortia to implement the learnings from EXAM. The goal is to make global collaborations like EXAM repeatable, sustainable, much faster and more effective. Ultimately, this will accelerate creation and deployment of AI algorithms that help clinicians tackle some of the most complex challenges in healthcare — applying the learnings from this pandemic to pressing unmet patient needs and other epidemics.

“The only way to bring model improvement into the clinical workflow is through federated learning,” said Dr. Quanzheng Li of the Gordon Center for Medical Imaging at Massachusetts General Hospital, who developed the initial model on which the EXAM study was based. “This will allow us to learn deep insights from the longitudinal patient pathway, both locally at a specific site and across any place the model is deployed.”

About EXAM Authors

First authors of the EXAM Study are Ittai Dayan, MD (Massachusetts General Hospital / Harvard Medical School), Aoxiao Zhong, PhD (Massachusetts General Hospital / Harvard Medical School), and Holger Roth, PhD (NVIDIA). Senior authors are Mona Flores, MD (NVIDIA), Fiona Gilbert, MD (University of Cambridge School of Medicine), and Quanzheng Li, PhD (Massachusetts General Hospital / Harvard Medical School). Many other authors from participating institutions contributed, and the full list is available here.

About Rhino Health

The Rhino Health Platform allows medical researchers and healthcare AI developers to seamlessly access diverse and disparate datasets and use them to create better AI algorithms. Grounded in federated learning, Rhino Health makes it possible to collaborate without ever moving data, transferring ownership or risking patient privacy. Headquartered in Boston, Massachusetts, Rhino Health is a growing team of healthcare and technology experts committed to accelerating creation and adoption of AI-based healthcare solutions for increasingly diverse patient populations.

Contact
Michelle Cox
[email protected]
+1 415-823-7574

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Clarivate Declares Dividend on Mandatory Convertible Preferred Shares

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LONDON, May 1, 2024 /PRNewswire/ — Clarivate Plc (NYSE: CLVT; CLVT PR A) (“Clarivate”), a leading global provider of transformative intelligence, today announced that its board of directors declared a quarterly dividend of $1.3125 per share on its 5.25% Series A Mandatory Convertible Preferred Shares (the “Preferred Shares”), payable in cash on June 3, 2024 to shareholders of record at the close of business on May 15, 2024.

On the mandatory conversion date, which is scheduled to occur on June 3, 2024, each Preferred Share will automatically and mandatorily convert into a number of ordinary shares of Clarivate (and cash in lieu of any fractional ordinary shares) based on the average volume weighted average price (“VWAP”) of Clarivate’s ordinary shares over a 30-trading day period that begins on, and includes, April 18, 2024 and is scheduled to end on, and include, May 30, 2024 (the “valuation period”). If such VWAP is (i) greater than $31.20, then the mandatory conversion rate will be 3.2052 ordinary shares of Clarivate per Preferred Share, (ii) less than or equal to $31.20 but equal to or greater than $26.00, then the mandatory conversion rate will be a number of ordinary shares of Clarivate per Preferred Share equal to $100.00 divided by such VWAP and (iii) less than $26.00, then the mandatory conversion rate will be 3.8462 ordinary shares of Clarivate per Preferred Share. The mandatory conversion rate will be announced following the end of the valuation period. The above description of the terms of the Preferred Shares is not complete and is subject to, and qualified in its entirety by reference to, the “Statement of Rights” for the Preferred Shares, which is filed as Exhibit 3.2 to Clarivate’s annual report on Form 10-K for the fiscal year ended December 31, 2023.
Cautionary Note Regarding Forward-Looking Statements
This communication contains “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995. These statements, which express management’s current views concerning future business, events, trends, contingencies, financial performance, or financial condition, appear at various places in this communication and may use words like “aim,” “anticipate,” “assume,” “believe,” “continue,” “could,” “estimate,” “expect,” “forecast,” “future,” “goal,” “intend,” “likely,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “see,” “seek,” “should,” “strategy,” “strive,” “target,” “will,” and “would” and similar expressions, and variations or negatives of these words. Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on management’s current beliefs, expectations, and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy, and other future conditions. These forward-looking statements involve a number of risks and uncertainties (some of which are beyond our control) or other assumptions that may cause actual results or performance to be materially different from those expressed or implied by these forward-looking statements. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include those factors discussed under the caption “Risk Factors” in our annual report on Form 10-K, along with our other filings with the U.S. Securities and Exchange Commission (“SEC”). However, those factors should not be considered to be a complete statement of all potential risks and uncertainties. Additional risks and uncertainties not known to us or that we currently deem immaterial may also adversely affect our business operations. Forward-looking statements are based only on information currently available to our management and speak only as of the date of this communication. We do not assume any obligation to publicly provide revisions or updates to any forward-looking statements, whether as a result of new information, future developments or otherwise, except as otherwise required by securities and other applicable laws. Please consult our public filings with the SEC or on our website at www.clarivate.com.
About Clarivate
Clarivate™ is a leading global provider of transformative intelligence. We offer enriched data, insights & analytics, workflow solutions and expert services in the areas of Academia & Government, Intellectual Property and Life Sciences & Healthcare. For more information, please visit www.clarivate.com.
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CGTN: 3rd CMG Forum in Beijing discusses AI development

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BEIJING, May 1, 2024 /PRNewswire/ — Focusing on the development of AI, the third CMG Forum was held on Monday in Beijing.

Li Shulei, a member of the Political Bureau of the Communist Party of China (CPC) Central Committee and the head of the Publicity Department of the CPC Central Committee, attended the opening of the event and delivered a speech.
Guests at the forum stressed the role of media in promoting the innovative application of AI as well as its governance.
Efforts should also be made to boost the development of AI in creating positive, healthy, diverse and high-quality content, so that AI can become a force for good and benefit mankind, they agreed.
They also called on media to accelerate intelligent transformation and help bridge international exchanges and cooperation on the governance of AI to facilitate its healthy, orderly and safe development.
Hosted by China Media Group (CMG), the forum attracted more than 200 participants from international organizations, media, think tanks and multinational companies.
“Innovation and breakthroughs in science and technology not only guide the development and progress of human civilization, but also bring uncertainty to the changing world,” said Shen Haixiong, vice minister of the Publicity Department of the CPC Central Committee and president of CMG. He called for efforts to jointly create valuable and responsible artificial intelligence.
AI technology is affecting every aspect of our lives. Thomas Bach, president of the International Olympic Committee (IOC), stated in a video speech that CMG has always been a partner of the IOC, bringing the charm of the Olympic Games to hundreds of millions of Chinese viewers. He said the IOC invites CMG to work together for the creation of a future with the application of AI in Olympic sports.
“From ancient inventions such as silk, printing and the compass to modern technological advances such as robotics, telecommunications and green technology, China has always been committed to innovation and creation,” said Daren Tang, director general of the World Intellectual Property Organization (WIPO). He said WIPO pays close attention to ensuring a balance between the opportunities and risks of artificial intelligence and is committed to strengthening cooperation to ensure that artificial intelligence is properly used.
https://news.cgtn.com/news/2024-04-30/3rd-CMG-Forum-in-Beijing-discusses-AI-development-1tdDcXvCexG/p.html

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Trianz Appoints Sridhar Kannan as Practice Leader – Digital, Elevating its Leadership in the Global Digital Transformation Space

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SANTA CLARA, Calif., May 1, 2024 /PRNewswire/ — Digital transformation technology & services company Trianz is pleased to announce the appointment of Sridhar Kannan as Practice Leader – Digital. With over 25 years of extensive experience in technology and business leadership, Sridhar joins Trianz to lead the expansion of Trianz’s Digital Practice, forging strategic alliances and expanding the business footprint.

Sridhar’s appointment comes at a transformative phase for Trianz as it solidifies its commitment to redefining the digital landscape with an “IP Led” model. This strategic shift is powered by Trianz’s cutting-edge hyper-automated platforms, Concierto.Cloud, Extrica.AI, and Pulse, driving industry-leading transformations in cloud, data and analytics, AI, and the digital workplace. Sridhar’s visionary leadership in technology-led business transformations across diverse sectors will be instrumental in leveraging IP-led models and innovative methodologies to position Trianz at the forefront of digital transformation.
“We are thrilled to welcome Sridhar Kannan to the Trianz family,” said Seshi Vanguru, Chief Revenue Officer at Trianz. “His appointment marks a significant stride in Trianz’s journey toward innovation and excellence. Sridhar’s wealth of experience and exceptional leadership skills will elevate our Digital Practice to new heights, reaffirming our commitment to delivering exceptional value to our clients.”
Sridhar is recognized as a client-focused technology and business transformation executive with a remarkable track record of helping Banking and Financial Services organizations in business transformation and product innovation using applications, cloud, data, and digital solutions. His extensive prior experience at industry giants such as Wipro, Cognizant, and Infosys include successfully leading Fortune 10 global client relationships and implementing transformative solutions across Banking, Financial Services, and Healthcare industries. Sridhar is highly regarded for his ability to lead global cross-functional teams, foster collaboration, and achieve aggressive business goals while consistently delivering high levels of client satisfaction.
“I am deeply honored to join Trianz and contribute to its mission of shaping the future through digital transformation,” said Sridhar. “Together, we will push the boundaries of what’s possible and drive meaningful impact for our clients in this rapidly evolving digital landscape.”
Based out of Minnesota, US, Sridhar has steered numerous clients towards success through the strategic application of Digital, Cloud, Product Engineering, Data, AI, and Application services, making him a seasoned strategist in today’s dynamic digital landscape. His appointment marks a significant milestone in Trianz’s journey to nurturing talent and delivering world-class solutions.
About Trianz
Trianz is a leading-edge technology platforms and services company that accelerates digital transformations at Fortune 100 and emerging companies worldwide in data & analytics, digital experiences, cloud infrastructure, and security. Our “IP Led Transformations” approach, informed by insights from a recent global study spanning 20+ industries and 5000+ companies, addresses challenges posed by the rapid pace of AI-driven transformation, digital talent scarcity, and economic uncertainty. Our IP and platforms, including Concierto, Extrica, and Pulse, revolutionize cloud adoption, data analytics, and AI insights, empowering organizations to navigate the complexities of digital transformation seamlessly.
Founded in California and with an organization of over 2,000 associates across the United States and India, Trianz is a Premier Partner of AWS, consistently rated #1 by clients for value delivery over the past five years. Trianz has been ranked as one of the best Consulting Firms by Forbes and has been certified as a Great Place to Work for three years in a row. To learn more about Trianz, email [email protected] or visit www.trianz.com.
Watch Trianz CEO Sri Manchala’s insightful interview with Bloomberg on Partner | Crossing The Digital Faultline & Leading Towards Transformative Success – YouTube and delve deeper into his book Crossing the Digital Faultline at Crossing the Digital Faultline | Trianz.
Trianz Media Team : [email protected]+1-408-387-5800
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