Artificial Intelligence
World’s First External Independent Randomized Controlled Trial of Artificial Intelligence Demonstrates More Accurate Colonoscopy Screening and Surveillance Utilizing Wision AI’s Technology Compared to the Standard of Care
– Data published in Clinical Gastroenterology & Hepatology indicate that the trial successfully shows the efficacy and safety of Wision AI’s artificial intelligence-based computer-aided polyp detection system during colonoscopy –
SHANGHAI, China, Sept. 29, 2021 (GLOBE NEWSWIRE) — Wision AI, a leader in developing computer-aided diagnostic algorithms and real-time systems to improve the accuracy and effectiveness of diagnostic imaging, today announced the publication of data demonstrating positive results and competitive advantages of using its artificial intelligence computer-aided polyp detection (CADe) system during colorectal cancer screening in a U.S. patient population. In this world’s first external independent randomized controlled trial (RCT) of AI in the medical field conducted in the United States (NCT03925337), 232 patients were enrolled for screening and surveillance colonoscopy in four leading U.S. academic institutions. Results indicated that the Wision AI‘s CADe device, EndoScreener, significantly reduced the adenoma miss rate (31.25% vs. 20.12%, p=0.0247) and increased adenoma detected per colonoscopy (0.90 vs. 1.19, p=0.0323). The trial data have been published in Clinical Gastroenterology & Hepatology.i
“Our study demonstrates that computer-aided polyp detection has the potential to decrease variability in colonoscopy quality among providers by reducing the miss rate even for experienced physicians,” said senior study author Tyler M. Berzin, MD, director of the Advanced Endoscopy Fellowship at Beth Israel Deaconess Medical Center. “While traditional colonoscopy already detects precancerous polyps earlier and more effectively than stool DNA tests and “virtual” CT scan colonography, the addition of AI polyp detection tools will further support the role of colonoscopy as the gold standard for colorectal cancer screening and prevention.”
This is the world’s first randomized controlled trial of AI technology to conclusively show generalizability by independent, external validation. Patients in the trial were randomly assigned to groups that received either AI-assisted colonoscopy or routine colonoscopy, followed immediately by the other procedure. Institutions involved in the dataset training were excluded from the trial. Investigators evaluated the efficacy of a colon polyp detection system derived from training data sets developed in China and demonstrated high performance of the algorithm in a U.S. patient population undergoing colorectal cancer screening and surveillance. Results indicated that the performance and efficacy of EndoScreener in the trial were consistent with the results of previous RCTs conducted in the originated institution.ii,iii,iv,v
“AI-based systems hold great promise in their ability to improve diagnostic imaging and ensure more accurate detection of adenomas and polyps missed during standard colonoscopy,” said Dr. Sophie Xiao, Chief Scientist of Wision AI. “However, the mathematical essence of deep learning algorithms may lead to the lack of generalization and robustness of AI systems that cannot be cured by increasing training data. The total development dataset of our algorithm contains less than 6000 images that are 100% from a single hospital in west China.vi The EndoScreener system was designed to overcome these challenges, and the data reported in the trial demonstrate that there was no observed performance discrepancy or observed ceiling effect of the system in four leading hospitals in the U.S. We believe that a well designed and rigorously conducted external independent RCT is an ultimate and necessary validation for medical AI applications and we are very pleased to see the positive results of the EndoScreener system in this trial.”
After the exclusion of nine patients, a total of 223 patients entered the study, of whom 59.6% were undergoing primary colorectal cancer (CRC) screening and 40.4% were undergoing post-polypectomy surveillance. Patients were randomized to either CADe (n=113) or HDWL colonoscopy (n=110) first, after which they immediately underwent colonoscopy using the other method. Key findings of the study include:
- A 20.12% AMR in the CADe-first group, compared with 31.25% in the HDWL-first group (p=0.0247).
- A 20.70% polyp miss rate (PMR) in the CADe-first group, compared with 33.71% in the HDWL-first group (p=0.0007).
- A 7.14% sessile serrated lesion (SSL) miss rate in the CADe-first group, compared with 42.11% in the HDWL-first group (p=0.0482).
- An APC of 1.9 in the CADe-first group, compared with 0.90 in the HDWL-first group (p=0.0323).
- The first-pass adenoma detection rate (ADR) was higher with observable difference in the CADe-first group (50.44%) vs. the HDWL-first group (43.64%) (p=0.309).
- Multivariate analysis identified randomization to HDWL-first, age ≤65 years old, and right colon vs. other location and factors significantly associated with missed adenomas (p=0.0214, p=0.0451, and p=0.0436, respectively).
About Wision AI
Wision AI has extensive expertise in mathematics and algorithm development. The company integrates medical knowledge into flexible and scalable models that leverage cutting-edge, convolutional neural networks and general-purpose computing to achieve stable detection efficacy in diagnostic imaging.
References
i Glissen Brown JR, Mansour NM, Wang P, et al. Deep Learning Computer-Aided Polyp Detection Reduces Adenoma Miss Rate: A U.S. Multi-Center Randomized Tandem Colonoscopy Study. Clin Gastrol & Hepatol. September 13, 2021. DOI: https://doi.org/10.1016/j.cgh.2021.09.009
ii Wang P, Berzin TM, Glissen Brown JR, et al. Real-time automatic detection system increases colonoscopic polyp and adenoma detection rates: a prospective randomised controlled study. Gut. 2019;68(10):1813-1819. doi:10.1136/gutjnl-2018-317500
iii Wang P, Liu X, Berzin TM, et al. Effect of a deep-learning computer-aided detection system on adenoma detection during colonoscopy (CADe-DB trial): a double-blind randomised study [published correction appears in Lancet Gastroenterol Hepatol. 2020 Apr;5(4):e3]. Lancet Gastroenterol Hepatol. 2020;5(4):343-351. doi:10.1016/S2468-1253(19)30411-X
iv Liu P, Wang P, Glissen Brown JR, et al. The single-monitor trial: an embedded CADe system increased adenoma detection during colonoscopy: a prospective randomized study. Therap Adv Gastroenterol. 2020;13:1756284820979165. Published 2020 Dec 15. doi:10.1177/1756284820979165
v Wang P, Liu P, Glissen Brown JR, et al. Lower Adenoma Miss Rate of Computer-Aided Detection-Assisted Colonoscopy vs Routine White-Light Colonoscopy in a Prospective Tandem Study. Gastroenterology. 2020;159(4):1252-1261.e5. doi:10.1053/j.gastro.2020.06.023
vi Wang, P., Xiao, X., Glissen Brown, J.R. et al. Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy. Nat Biomed Eng 2, 741–748 (2018). https://doi.org/10.1038/s41551-018-0301-3
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Helena Nimmo appointed CIO and Debra McCowan appointed CHRO to fuel IFS’s next phase of growth in pioneering and dominating Industrial AI
LONDON, Oct. 7, 2024 /PRNewswire/ — IFS, the leading provider of enterprise cloud and Industrial AI software, has made two senior appointments to its Executive Board. Helena Nimmo joins as global Chief Information Officer (CIO) and Debra McCowan as Chief Human Resources Officer (CHRO).
Nimmo joins from Endava, a US-listed global technology company with over 12,000 employees. As CIO at IFS, Nimmo will engage CIOs and tech leaders at IFS customers to help them with their strategic transformation journeys, as well as driving the effective application of technology within IFS to deliver better products and services to customers. With IFS leading the adoption of Industrial AI across the world, Nimmo will drive the integration of AI across the IFS community, enabling IFS customers to deliver exceptional moments of service to their clients.
McCowan was CHRO at NetApp, Inc., a Fortune 500 global data infrastructure, AI and cloud services company. In this board level role, McCowan was a strategic partner and advisor to the CEO and executive leadership team. As IFS rapidly grows beyond 7,000 employees in over 90 countries, McCowan will build on the HR transformation strategy IFS has already embarked on, to lead a high-performing global team, delivering progressive HR strategies and initiatives to rapidly grow and scale IFS’s footprint.
“I’m delighted that Helena and Debra are joining IFS at such a pivotal point in its growth journey,” said Mark Moffat IFS CEO. “Helena’s leadership has been instrumental in orchestrating company-wide transformations, developing core technology infrastructures, and implementing robust security measures. Debra is a transformational Human Resources executive with years of global leadership experience in the technology sector, making her an excellent fit for this role. I look forward to the new perspectives and ideas they will both bring to IFS and support our global mission to lead the Industrial AI revolution.”
Nimmo started her career at Nokia in Finland and has since held leadership positions in both customer-facing and internal technology functions at organizations including Symbian, Fujitsu and Thomson Reuters.
“I’m delighted to be joining IFS, the world leader in cloud enterprise software and Industrial AI,” said Nimmo, IFS’s CIO. “I am excited to add my expertise to drive digital innovation and deliver exceptional value to our customers. I have a passion for technology and a commitment to excellence and am eager to contribute to IFS’s continued growth and success.”
Prior to NetApp, McCowan was the CHRO at Equinix the world’s leading global data center and interconnection provider. She has held global executive leadership roles at Avago Technologies (now Broadcom Inc.), Hitachi Data Systems (now Hitachi Vantara), and Telstra Corporation.
“Joining IFS at a time of significant growth globally is a tremendous opportunity,” said Debra McGowan, IFS CHRO. “My mission is to continue to build a conducive environment for diverse, strategically aligned high performing teams to connect and thrive in a fast-paced business and in a dynamic workplace. I look forward to this exciting challenge.”
About IFS
IFS is the world’s leading provider of Industrial AI and enterprise software for hardcore businesses that make, service, and power our planet. Our technology enables businesses which manufacture goods, maintain complex assets, and manage service-focused operations to unlock the transformative power of Industrial AI™ to enhance productivity, efficiency, and sustainability.
IFS Cloud is a fully composable AI-powered platform, designed for ultimate flexibility and adaptability to our customers’ specific requirements and business evolution. It spans the needs of Enterprise Resource Planning (ERP), Enterprise Asset Management (EAM), Supply Chain Management (SCM), Information Technology Service Management (ITSM), and Field Service Management (FSM). IFS technology leverages AI, machine learning, real-time data and analytics to empower our customers to make informed strategic decisions and excel at their Moment of Service™.
IFS was founded in 1983 by five university friends who pitched a tent outside our first customer’s site to ensure they would be available 24/7 and the needs of the customer would come first. Since then, IFS has grown into a global leader with over 7,000 employees in 90+ countries. Driven by those foundational values of agility, customer-centricity, and trust, IFS is recognized worldwide for delivering value and supporting strategic transformations. We are the most recommended supplier in our sector. Visit ifs.com to learn why.
Contact information:EUROPE / MEA / APJ:Adam GillbeEmail: [email protected]
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Artificial Intelligence
Transforming Real Estate: Deka Immobilien and BuildingMinds Join Forces to Create Centralized ESG Data Hub for Carbon Reduction
BERLIN, Oct. 7, 2024 /PRNewswire/ — Deka Immobilien is implementing a central ESG data platform for its entire global real estate portfolio with BuildingMinds, the GRI winner of Proptech of the Year 2024. In the future, all stakeholders, from property and asset management to portfolio management, will be able to make data-driven decisions in real-time concerning the buildings and their CO2 emissions. At the same time, the created database will become the central supplier for Deka Immobilien’s ESG reporting activities.
The BuildingMinds platform is intended to serve as a control instrument, primarily for reducing the CO2 emissions of existing buildings.
A good, reliable database is the starting point for a well-founded reduction of CO2 emissions. BuildingMinds supports Deka Immobilien by providing structured data collection methods for energy and media consumption that meet the demands of a global real estate portfolio with varying requirements in individual countries and across different types of building usage. In addition, ESG-relevant documents such as energy certificates, green building certificates, and other expert opinions can be linked to each building. Enriched by a data quality assurance process, including a digitized, comprehensible filling of any data gaps, the platform becomes the “single-source-of-truth” for planning and reporting systems at Deka Immobilien.
The acquired database will become a central component in creating transparency around Deka Immobilien’s actions and the foundation for meeting European ESG reporting requirements. The BuildingMinds platform is integrated into Deka Immobilien’s reporting processes and also supports evaluations regarding the taxonomy conformity of the portfolio.
In the active asset management of the properties, the platform is used as an optimization tool. In the future, property, asset, and portfolio managers should be able to validate planning decisions based on real-time data. Benchmarks for energy and CO2 emissions can be used to analyze individual assets and entire portfolios. Targeted action plans can be evaluated in terms of their impact on energy, CO2 emissions, investment, and operating costs, allowing the path to achieving climate goals to be aligned with the fiduciary responsibility towards investors.
About BuildingMindsFounded in 2018 and fully funded by the Schindler Group, BuildingMinds is a software-as-a-service (SaaS) provider for the real estate industry, offering a comprehensive, data-driven platform for improving building performance. Using innovative technologies and analytics, BuildingMinds enables property owners and managers to efficiently monitor, assess, and optimize their portfolios and assets. This supports the development of a more sustainable and data-driven transformation in the real estate industry.
International Press Enquiries: Peter PanayiHead of Go-To-Market & Global Communicaions+44 [email protected]
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Artificial Intelligence
Racing Legend Jacques Villeneuve Engages CYPFER to Embolden Cybersecurity & Digital Resilience
Villeneuve Looks to Be a Living Demonstration of Futurizing Racing Brands and The Business of Motorsports
MIAMI, LONDON and TORONTO, Oct. 7, 2024 /PRNewswire/ — Jacques Villeneuve, former Formula 1 World Champion and current F4 team owner, announced today the strategic partnership with Daniel Tobok, CEO of CYPFER, as Chief Cyber Intelligence Advisor for Villeneuve’s racing teams.
“The integration of advanced technology in motorsports demands equally advanced cybersecurity measures,” says Daniel Tobok, CEO of CYPFER. “With Jacques Villeneuve’s teams pushing the limits of innovation, we are dedicated to protecting their digital infrastructure, ensuring data integrity, and maintaining competitive advantage,” states Tobok.
The motorsports industry is increasingly reliant on digital technology, from car telemetry to race strategy simulations. According to a report by Cybersecurity Ventures, the cybercrime epidemic is predicted to cost the world $10.5 trillion annually by 2025, with the sports sector being a significant target due to its high-profile nature and valuable data.
“Racing at the highest levels requires not only physical and mechanical excellence but also digital security,” says Jacques Villeneuve. “Partnering with CYPFER gives us the confidence that our sensitive data, from race strategies to telemetry, is secure from cyber threats. This collaboration is a crucial part of our commitment to our core mission: winning races and pushing the boundaries of what’s possible in motorsports,” concludes Villeneuve.
“Entering the world of motorsports with Jacques Villeneuve is an exciting milestone for CYPFER,” shares Tobok. “Jacques’ legacy in racing and his forward-thinking approach make him an ideal collaborator. We are ready to safeguard his teams’ digital assets and contribute to their continued success,” concludes Tobok.
About CYPFER
CYPFER is on a global mission to help companies create Cyber Certainty™. With an experienced team of incident responders, threat researchers, seasoned ransom experts, and data restoration experts, CYPFER is the trusted firm for leading law firms, insurance carriers and global organizations. CYPFER’s cybersecurity professionals are located across the US, Canada, UK, and Caribbean. The CYPFER team is ready to respond and help clients experiencing cyber attacks 24x7x365. CYPFER’s experts provide white-glove service and aim to restore Cyber Certainty™ for all clients on every engagement.
CYPFER’s core services include:
Ransomware Advisory Incident Response Services with specialized expertise in ransomware response and recoveryOn-site and/or remote post-breach restoration support to augment internal teamsCYPFER is headquartered in Miami, FL. The company currently employs 140+ cybersecurity experts and has supported clients across six continents. CYPFER is executing plans to expand across the globe and boast a workforce of 200 cybersecurity professionals by the end of 2024.
For inquiries, please contact our PR Team at [email protected]
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