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Presented at SCCT – New Plaque Clinical Data Provides Additional Insights on Anatomy and Physiology in Clinical Decision Making for Patients

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MOUNTAIN VIEW, Calif., July 21, 2022 (GLOBE NEWSWIRE) — HeartFlow, Inc., the leader in revolutionizing precision heart care, released two datasets utilizing its HeartFlow AI-based Plaque technology* (referred in below as “HeartFlow Plaque”). The first dataset – HeartFlow’s largest study to date – studied over 11,800 patients and enables physicians to understand a patient’s burden of coronary plaque compared to their age and sex-matched peers. The second dataset demonstrated that HeartFlow Plaque* may be “a reasonable non-invasive alternative to invasive angiography for assessment of coronary plaque”.1 Both studies were presented at the 17th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography (SCCT) in Las Vegas, NV, July 15-17th, 2022.

The “Nomographic CT Quantitative Plaque Data from a Large International Population”, presented by Georgios Tzimas, MD, University of British Columbia, Providence Health Care supported the clinical utility of being able to distinguish patients with high or low volumes of plaque across a population. HeartFlow Plaque* was applied to over 11,800 coronary computed tomography angiograms (CCTAs) and atherosclerotic plaque burden data were stratified by age and sex. Understanding how an individual patient’s plaque volume compares to that of the general population can provide context for physicians as they consider the best treatment plan for an individual patient. The information may also help motivate patients to adhere to recommended medications or lifestyle modifications.

The “Quantitative Assessment Of AI-based CCTA Plaque Volume Compared With IVUS2” presentation by Kersten Petersen, PhD, Senior Manager, Research, showed that HeartFlow Plaque* agreed well with intravascular ultrasound (IVUS) measures of plaque volume (correlation coefficient of 0.92). This confirms that HeartFlow Plaque* from CCTA is accurate when compared to IVUS and shows a strong correlation across a wide range of plaque volumes and types. By accurately quantifying the amount of plaque present in a patient’s coronary arteries, physicians can be provided with meaningful quantitative plaque information from CT images.

“We’ve known for years that atherosclerosis and coronary risk are multifactorial, reflecting aspects both of plaque burden and composition, as well as physiological influences. Understanding both plaque burden and physiology are imperative to assessing patient risk and optimizing treatment plans for patients with coronary artery disease,” said Campbell Rogers, MD, FACC, Chief Medical Officer, HeartFlow. “The new data reflect the company’s belief in the value of precise plaque information being additive to the critical physiological data we provide through FFRCT. We look forward to introducing HeartFlow Plaque* and working with physicians to understand better the interplay of plaque and physiology across the spectrum of coronary disease.”

*Currently pending 510(k) clearance from the Food and Drug Administration (FDA). Not available for sale.

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About the HeartFlow FFRct Analysis

Starting with a standard coronary computed tomography angiogram (CCTA), the HeartFlow Analysis leverages algorithms trained using deep learning (a form of AI) and highly trained analysts to create a digital, personalized 3D model of the heart. The HeartFlow Analysis then uses powerful computer algorithms to solve millions of complex equations to simulate blood flow and provides FFRct values along the coronary arteries. This information is used by physicians in evaluating the impact a blockage may be having on blood flow and determine the optimal course of treatment for each patient. A positive FFRct value (≤0.80) indicates that a coronary blockage is impeding blood flow to the heart muscle to a degree which may warrant invasive management.

Data demonstrating the safety, efficacy and cost-effectiveness of the HeartFlow Analysis have been published in more than 500 peer-reviewed publications, including long-term data out to five years.1 The HeartFlow Analysis offers the highest diagnostic performance available from a non-invasive test.3 To date, clinicians around the world have used the HeartFlow Analysis for more than 130,000 patients to aid in the diagnosis of heart disease.1

About HeartFlow Plaque* Overview

The HeartFlow Plaque* overview will provide plaque volume and characterize the type of plaque present. The HeartFlow Plaque* feature is based on a fully automated deep-learning (a form of AI) algorithm for characterizing and quantifying plaque. In an internal study, the HeartFlow Plaque* technology was found to be more reliable than expert CT readers in identifying different types of plaque and quantifying total plaque volume.4 By adding the plaque overview to the physiological information currently provided by the HeartFlow Analysis, physicians will gain a more comprehensive understanding of a patient’s coronary disease burden and support efficient risk stratification of patients who may be at high risk of death from a heart attack.

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About HeartFlow

HeartFlow is the leader in revolutionizing precision heart care, uniquely combining human ingenuity with advanced technology. HeartFlow’s non-invasive HeartFlow FFRct Analysis leverages artificial intelligence to create a personalized three-dimensional model of the heart. Clinicians can use this model to evaluate the impact a blockage has on blood flow and determine the best treatment for individual patients. HeartFlow’s technology is reflective of our Silicon Valley roots and incorporates over two decades of scientific evidence with the latest advances in artificial intelligence. The HeartFlow FFRct Analysis is commercially available in the United States, UK, Europe and Japan. For more information, visit www.heartflow.com.

Contact

For Investors:
Leigh Salvo or Jack Droogan
Gilmartin Group
[email protected]

For Media:
Linly Ku
HeartFlow
[email protected]

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  1. Data on file at HeartFlow
  2. Multi-modality Imaging in Acute Myocardial Infarction (MIAMI), Robert Safian, MD, Beaumont Hospital, Royal Oaks, MI
  3. Driessen, et al. J Am Coll Cardiol 2019; Norgaard, et al, Euro J Radiol 2015
  4. HeartFlow Formal Reproducibility Study. December 2021

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Artificial Intelligence

sCrypt Launches Chain-Agnostic Developer Platform for UTXO Blockchains

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SAN FRANCISCO, July 1, 2024 /PRNewswire/ — sCrypt, a full-stack Web3/blockchain development platform, has announced the launch of its groundbreaking developer tool kit designed for the Unspent Transaction Output (UTXO) blockchains. The new tools will revolutionise how developers interact with UTXO blockchains, making them more accessible and fostering creativity in the Web3 space. 

UTXO is the method the Bitcoin protocol uses to track balances as they move between digital wallets. The UTXO model is essential for maintaining the security and integrity of blockchain networks and solves the double-spend problem. 
The sCrypt platform provides comprehensive toolkits such as Software Development Kits (SDK) and Application Programming Interfaces (APIs) that allow developers to seamlessly integrate UTXO blockchains into their applications. The platform will also integrate a vast ecosystem of JavaScript/TypeScript developers, estimated at 13 million globally. These developers can now leverage their existing skills to build and operate on UTXO blockchains. 
By doing so, sCrypt opens a world of opportunities, where developers are equipped with the best tools to drive innovation and success. 
The SDK provides libraries in various languages, detailed documentation, and tutorials and offer a flexible and robust framework for leveraging payments, tokens, and smart contracts. Whereas APIs allow developers to read from and write into blockchains, without setting up and maintaining their own nodes and indexers. As a tool kit, they allow developers to focus on the business logic of their dApp (decentralised applications), rather than worrying about the underlying blockchain infrastructure.
The platform is chain-agnostic, allowing developers to focus all their intellectual horsepower on application development rather than blockchain specifics. This industry-first platform is designed to power Web3 growth and empower developers to build and scale their dApp efficiently and effortlessly, by leveraging UTXO’s unparalleled scalability and programmability. 
Xiaohui Liu, Founder and CEO at sCrypt said, “Historically, Web3 applications have been largely built on account-based blockchains like Ethereum and Solana. Ordinals have brought renewed development interest back to Bitcoin and UTXO blockchains. With our extensive developer tooling and infrastructure, it is now easier than ever to build on UTXO blockchains, empowering builders to unleash UTXO’s superior scalability and programmability.”
Companies utilising the sCrypt platform include BTC platforms, such as Dotswap, the first BRC20 token swap platform on BTC, offer fast and seamless token exchanges, leveraging a fully functioning Automated Market Maker (AMM) and liquidity pools. It uses sCrypt’s APIs to query the status of tokens, including BRC20 and Runes. TierTopis another cutting-edge BTC trading platform that supports Ordinals NFTs, BRC-20 tokens, and bitmaps which rely on sCrypt’s token APIs.
Other businesses using sCrypt include Tokenovate, which leverages sCrypt’s smart contracts to manage trading lifecycle events of derivatives, such as interest-rate swaps and voluntary carbon credits. Additionally, various innovative applications benefiting from sCrypt’s toolkit are Hodlocker, Order Lock by RelayX, Tokenized, 1Sat Ordinals and Yours Wallet. 
The sCrypt platform is poised to be a game-changer for developers working within the UTXO framework, offering them resources to develop next-generation blockchain applications and aiming to become the de-facto development platform for UTXO blockchains. 
About sCrypt:sCrypt is a UTXO-blockchain development platform that offers a suite of tools and infrastructure to enhance and accelerate the development process of decentralised applications (dApps). It provides a rich set of APIs and software development kits (SDKs) that simplify blockchain interactions, such as querying blockchain data, sending transactions, issuing tokens, and developing smart contracts. It specialises in UTXO blockchains and supports multiple of them, such as Bitcoin and Bitcoin SV.
 

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Artificial Intelligence

ALLATRA President Discussed Climate Change with Pope Francis

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The Pope received the President of ALLATRA in an audience at the Vatican
VATICAN CITY, July 1, 2024 /PRNewswire/ — Pope Francis hosted distinguished scientists and experts from various countries and disciplines at a private audience at the Apostolic Palace in Vatican City. The selected attendees were participants in the Three-day International Conference on ‘Generative Artificial Intelligence and Technocratic Paradigm,’ organized by the Centesimus Annus Pro Pontifice Foundation (CAPP) – operating within the Secretariat of State of the Holy See and led by the esteemed Chairwoman, Dr. Anna Maria Tarantola.

Among the invited guests were Dr. A. Egon Cholakian, a National Security Expert, Washington D.C. Governmental Affairs Advisor to the ALLATRA International Public Movement, CAPP Foundation member; and Maryna Ovtsynova, President of the ALLATRA International Public Movement.
During the audience at the Vatican, the President of ALLATRA presented to Pope Francis a climate report ‘On The Progression Of Climatic Disasters On Earth And Their Catastrophic Consequences.’ In their personal conversation, she raised the issue of climate change as a global problem, emphasizing that it represents one of the most pressing challenges for humanity.
During the conversation, Pope Francis listened attentively and expressed his pleasure in offering his blessing to the ALLATRA International Public Movement. Following the event, Maryna Ovtsynova, President of ALLATRA, also personally received a blessing from the Holy See and Pope Francis on this significant day for the ALLATRA organization.
Additionally, the international conference featured discussions on technological innovations that are set to shape the future of civilization.
Since the future of humanity will be played out on the front of technological innovation, Pope Francis stated, “We must not miss the opportunity to think and act in a new way, with mind, heart and hands,” in order to “direct innovation toward a configuration centred on the primacy of human dignity.” – cites ‘Vatican News.’
During the event, in a pivotal discussion with conference organizers, Maryna Ovtsynova, President of the ALLATRA International Public Movement, addressed the pressing global threats to freedom and democracy. Mrs. Ovtsynova addressed the ongoing investigation into the illegal persecution of ALLATRA participants in several countries with low democracy indexes. Specifically, she detailed how they were subjected to a defamation campaign initiated by a Russian anti-cult organization. Additionally, she mentioned that this defamation campaign occurred not only in Russia but also in Ukraine, which indicates the significant influence of the Russian anti-cult organization on Ukraine.
During the conversation, Maryna Ovtsynova also raised the issue that anti-cult organizations, which exist contrary to democratic norms, cast a shadow on faith and on what Christianity stands for—freedom of religion and freedom of conscience.
During an audience on June 22, 2024, Maryna Ovtsynova expressed heartfelt gratitude to Pope Francis for his significant contributions as a responsible and decisive leader in the social integration of the Roman Catholic Church and for strengthening its role in contemporary secular society. She also thanked him for his kindness, warmth, and support during this special moment for ALLATRA.
Photo – https://mma.prnewswire.com/media/2451854/ALLATRA_Pope_Francis_Maryna_Ovtsynova.jpgPhoto – https://mma.prnewswire.com/media/2451855/Vatican_ALLATRA_collage.jpg

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35 Institutions Recognised for Excellence in Education and Innovation in the 2024 Anthology Catalyst Awards

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BOCA RATON, Fla., July 1, 2024 /PRNewswire/ — Anthology, the leading provider of education solutions that support the entire learner lifecycle, today announced the winners of the 2024 Catalyst Awards. The awards honour those driving innovation and excellence within higher education. Winners are recognised across 8 categories and selected by a cross-functional team of Anthology experts and represent the very best in their field.

This year, 35 winners were selected from among 108 nominees from institutions across 19 countries. Honourees will be recognised at the upcoming Anthology Together conference, one of the world’s largest EdTech conferences, taking place July 15-17 in Orlando, Florida.
“The Catalyst Awards celebrate what’s at the heart of higher education and technology – working together to drive student success. It’s inspiring to see the creative programmes and remarkable outcomes,” said Bruce Dahlgren, Chief Executive Officer at Anthology. “I am personally honoured to work with such an incredible community of innovators and educators as we partner together to deliver bold solutions to meet the needs of students and those who support them.”
The 2024 Anthology Catalyst Award winners by category:
Assessment & Institutional Effectiveness: This award recognises institutions that have successfully grown in their assessment practices and influenced positive behavioural changes using Anthology solutions.
Keiser University – Online Division, United States of America: The Online Academic Team – Sherry Olsen, Neha Prakash, and Marcel LarondeOdessa College, United States of America: Institutional Effectiveness Division – Connie MayUniversity of Cincinnati, United States of America: Traci SteehlerUniversity of the District of Columbia, United States of America: The Center for the Advancement of Learning & The Office of Planning and Institutional EffectivenessDiversity, Equity, Inclusion, and Belonging: This award honours those institutions leveraging technology to foster diversity, equity, inclusion, and belonging practices using Anthology solutions to ensure that their services are fully inclusive and supportive of all learners.
Grupo Ser Educacional, Brazil: EaD Management – Janyo Diniz, Joaldo Diniz, Enzo Moreira, Francislene Hasmann, and Sergio MuriloUniversity of Bahrain, Kingdom of Bahrain: Dr. Mazen AliUniversity of Derby, United Kingdom: PLT: Digital Learning and Online Content TeamUniversity of Illinois Chicago, United States of America: Landen DixonInstitutional Advancement: This award recognises institutions that have made significant changes to enhance the alumni and donor experience using Anthology solutions.
Morehead State University, United States of America: Alumni Relations & Development: Jessi Ferguson, Allie Rayburn, and Sherry SurmontUniversity of Louisville, United States of America: Communications & Marketing – Jessica Watts and Natalie TracyUniversity of Washington, United States of America: University AdvancementLeading Change: This award recognises institutions at the forefront of educational innovation that have used Anthology solutions to implement transformational initiatives that generate change on campus and in their academic ecosystems, with measurable results.
Central Michigan University, United States of America: The Office of Curriculum and Instructional Support – Marnie RoestelGrand Valley State University, United States of America: GVSU eLearning TechnologiesNorthumbria University, University of Southampton, College of DuPage, and WSU Tech, United Kingdom and United States of America. International Ally User Group: Kristen McCartney-Bulmer, Northumbria University; Matthew Deeprose, University of Southampton; Krystal Iseminger, WSU Tech; and Lara Tompkins, College of Du PageImam Abdulrahman Bin Faisal University, Kingdom of Saudi Arabia: Deanship of eLearning and Distance Learning – Dr. Muneerah B. AlmahasheerMapúa Malayan Colleges Laguna, Philippines: Mapúa Laguna 4Cers – Dr. Dodjie S. Maestrecampo, Anthony Hilmer S. Medrano, Maribel G. Songsong, Dr. Ramachandra C. Torres, Christian Dominic V. Kare, and John Mark L. AlmarezStudent Experience: This award recognises institutions leveraging technology to develop educational and administrative innovations that positively influence the total learner experience – outside and inside the classroom – and improve operational efficiency.
California Polytechnic State University, United States of America: Division of Student AffairsEdge Hill University, United Kingdom: Learning Design and Student Life TeamsMarshall University, United States of America: Enrollment Management – Dr. Jerry Ross, Dr. Beverly Boggs, and Nathan MillerSam Houston State University, United States of America: Student Involvement – Dr. Meredith Conrey and Emily FigueroaThe University of Memphis, United States of America: Dr. MK TylerStudent Success: This award recognises institutions whose innovative use of Anthology solutions has led to increased retention, increased completion, or improved outcomes through the implementation of new academic and administrative resources, data analytics solutions, scalable advising and intervention strategies and student support programmes.
Bellevue University, United States of America: College of Engineering, Technology and Management – Dr. Matthew Davis, Rebecca Barnes, and Nathan KraftJenison Innovation Academy (JIA), United States of America: JIA Leadership Team – Cameron Kuiper, Dr. Rebekah Redmer, and Krista OsterbergNorthern Border University, Kingdom of Saudi Arabia: Deanship of E-Learning and Knowledge Resources – Dr. Saud Abdul Mohsen Al-Muqahim, Dr. Sultan Munadi Al-Anazi, and Dr. Ghanim Tawash AlAnaziUniversity of Florida, George Mason University, and University of North Carolina at Charlotte, United States of America:  Shared Metacognition Team: Dr: Larisa Olesova, University of Florida; David Miller, George Mason University; and Dr. Ayesha Sadaf, University of North Carolina CharlotteTeaching & Learning: This award recognises institutions that have used Anthology solutions in innovative ways to advance learning.
Beacon Red, United Arab Emirates: Knowledge Systems Team – Phil Burgess, Sean McGuinness, Anurag Patel, and Jimmy JosephTechnical and Vocational Training Corporation, Kingdom of Saudi Arabia: E-Learning Center – Abdullah Farhan Aljably and Abdullah AldukhayyelThe University of Texas at El Paso, United States of America: The Center for Instructional DesignUniversidad Abierta Interamericana, Argentina: Faculty of Information Technology – Dr. Marcelo Edgardo De Vincenzi Zemborain, Nicolás Battaglia, and Dr. Carlos NeilWestern Kentucky University, United States of America: IDST 100 Course Development Team – Catie Weaver, Alicia Pennington, Ara Sprouse, and Brittney SholarTraining & Professional Development: This award recognises institutions that display an organisation-wide dedication to innovative training and development programmes for their educators and staff.
William Paterson University, United States of America: The Center for Teaching with Technology – Dr. Jae KimUniversidad Peruana de Ciencias Aplicadas, Peru: Diseño de entornos de aprendizaje DEA – DADO Team – Jessica Vlasica, Milagros Suyo, and Nancy OlmosUniversity of Central Oklahoma, United States of America: Center for eLearning and Connected Environments – Darren DenhamUniversity of Pretoria, South Africa: E-Education GroupWichita State University, United States of America: Office of Instructional ResourcesFor more information on the 2024 Catalyst Award winners, the full list of nominees, and complete category descriptions, please visit www.anthology.com/catalystawards.   
About Anthology
Anthology offers the largest EdTech ecosystem on a global scale for education, supporting more than 150 million users in 80 countries. With a mission to provide dynamic, data-informed experiences to the global education community through Anthology Intelligent Experiences™, we help learners, leaders and educators achieve their goals by offering over 60 SaaS products and services designed to advance learning. Discover more about how we are fulfilling our mission for education, business and government institutions at www.anthology.com.
Media Contact: Erin Mitchell, Director of Communications, Anthology. [email protected]
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