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FL Entertainment: 9M 2022 results

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Press Release

Paris – November 30th, 2022

9M 2022 RESULTS

STRONG REVENUE GROWTH,
HIGH PROFITABILITY AND CASH FLOW CONVERSION

9M 2022 FIGURES

  • Revenue growth: €2,713m, up +15.0% on a reported basis and +12.0% at constant exchange rates
  • Adjusted EBITDA1: €446m, up +17.5% versus 9M 2021, leading to 40bp margin increase to 16.5%
  • Adjusted net income: €210m up +15.4% versus €182m for the first 9M 2021
  • Net income: -€75m (9M 2021: -€2m) due to one-off impact from Group re-organization and listing
  • Adjusted free cash flow1: €369m, representing a cash flow conversion of 83%
  • Net financial debt / Adj. EBITDA2 ratio: improved to 3.4x as of September 30, 2022 versus 3.7x as at December 31, 2021, in line with 2022 guidance

9M 2022 HIGHLIGHTS

  • Content production & distribution
    • Revenue up +13.8%3 with a return to normalized pre-covid seasonality in Q3 2022
    • 11 bolt-on acquisitions4, support growth of international footprint and attract new clients
    • Content catalog: +25% increase in hours in catalog versus 9M 2021
  • Online sports betting & gaming
    • Revenue from continuing operations5: +12.9% with a strong recovery in Q3 2022 following quieter sports calendar in H1 2022 vs H1 2021
    • Unique Active Players up +11% in 9M 2022 versus 9M 2021
    • Targeting highest responsible gaming standards, launched major campaign in France
  • Group balance sheet strength:
    • Liquidity position: €547m
    • Financial debt at fixed rate with no maturity before 2025
    • S&P credit rating on Banijay6 upgraded to B+ in September 2022

François Riahi, CEO of FL Entertainment, said:

“FL Entertainment delivered strong Group revenue growth for the first nine months of 2022, demonstrating continued high profitability and cash generation.

In Content production & distribution, we saw a return to normalized seasonality in Q3 2022 with strong activity across existing and new unscripted formats, as well as attractive new scripted programming including Marie-Antoinette in France and SAS Rogue Heroes in the UK. Distribution revenues were also up across both broadcaster and streaming platforms. We also successfully executed 11 bolt-on
acquisitions this year so far, which will continue to drive performance and business development going forward.

Our Online sports betting & gaming business performed very well also, with an outstanding earnings growth, driven by its appealing digital platform and lean cost structure. With an 11% growth in unique active players year on year, Betclic is well placed to capitalize on opportunities from the football world cup, underpinned by its robust commitment to the highest standards of responsible gaming.

In an inflationary environment with several macroeconomic challenges, FL Entertainment is focused on driving productivity gains, particularly in content production, to protect margins and strong cash generation levels. The positive momentum seen in the year to date, combined with our leading positions in attractive and growing segments of the entertainment industry, puts us in a strong position to maintain continued sustainable growth in line with our 2022 guidance and mid-term outlook.”

*****

FL Entertainment invites you to its first 9M 2022 results conference call on:

Wednesday, November 30th 2022, at 6:00pm CET

Webcast live:
You can watch the presentation on the following link:
https://edge.media-server.com/mmc/p/7symqgxu

Dial-in access telephone numbers:
You need to register to the following link:
https://register.vevent.com/register/BI47798600cde24daaac9dc0b432e7a3f7

Slides related to 9M 2022 results are available on the Group’s website, in the “Investor relations” section:
https://fl-entertainment.com/investor-relations/

On 29 November 2022, the board of directors approved the financial report and the unaudited condensed financial statements for the first nine months 2022.

Accounts are presented under IFRS standards, unless explicitly mentioned

KEY FINANCIALS IN 9M 2022

€m 9M 2021 9M 2022 % change % constant currency
         
Group revenue 2 359.3 2 712.9 15.0% 12.0%
Adjusted EBITDA 379.8 446.4 17.5%  
Adjusted EBITDA margin 16.1% 16.5%    
         
Net income (1.8) (75.4)    
Adjusted net income excl. one-off items related to the transaction 181.8 209.8 15.4%  
         
Adjusted free cash-flow 303.3 368.9 21.6%  
Free cash flow conversion rate 80% 83%    
         
For the twelve-month period ended 31-Dec-21 30-Sep-22 % change  
         
Net financial debt (reported) 2 268.8 2 271.8 0.1%  
Net financial debt / Adjusted EBITDA 3.7x 3.4x    

FIRST 9M 2022 – KEY EVENTS

Business combination

On 10 May 2022, F.L. Entertainment N.V., announced that it had entered into a definitive business combination agreement with Pegasus Entrepreneurial Acquisition Company Europe B.V., a special purpose acquisition company, to become a listed company on Euronext Amsterdam.

The business combination was completed on July 1, 2022 and provided the Group with additional capital of around €608m after deduction of the fees and expenses of the Business Combination, estimated at approximately €35m. The first day of trading on Euronext Amsterdam took place on 1st July 2022.

Group reorganization

The Group conducted reorganization between entities within Financière Lov group and with minority interests in order to achieve the transaction described above. For more details, please refer to Note 3.1.2 to the Condensed Financial Statements for the 9-month period ended 30 September 2022.

Liquidation of Bet-at-home Entertainment Ltd

On 22 December 2021, Bet-at-home Group announced the liquidation of Bet-at-home Entertainment Ltd, a Maltese entity operating casino activities under license by the Malta Gaming Authority, consolidated at 53.9% as of December 2021, which took effect in the first half of 2022.

Content production & distribution acquisitions

Banijay maintained its acquisition strategy in 2022, realizing 11 bolt-on acquisitions7 of well-known production companies in the year to date across both non-scripted and scripted content. The strategic objective is to enrich Banijay’s content and geographical footprint, permanently increasing value to its customers thanks to its enlarged high-quality catalog. This strategy also creates economies of scale and contributes to long-term performance.

Companies acquired during the period strengthen Banijay’s exposure in 8 countries – the US, Australia, Israel, the UK, Germany, Italy, Spain and France – and adds expertise across unscripted, kids & family and premium scripted activities:

  • Légende Films (renamed Montmartre Films) is a high-profile filmmaker in France;
  • Znak TV, an entity created by famous showrunner and executive producer on Fox’s “MasterChef” amongst other large-scale entertainment brands, which operates in the US and the UK;
  • Groenlandia, an Italian premium scripted producer;
  • Tooco a specialist in the creation, development and management of new formats for the French and international markets;
  • Pookepsie Films is one of the most unique scripted production companies in Spain focused on the fantasy, thriller, and horror space;
  • UK young adult and family drama specialists, Kindle Entertainment;
  • Movimenti, an Italian production company and animation focused creative hub;
  • SONY Pictures Film-und Fernsehen GmbH in Germany is a home for high-quality, standout entertainment formats and scripted productions.

POST-CLOSING EVENTS

Content production & distribution acquisitions

Banijay realized 3 new acquisitions post-9M 2022, as it continued to expand its footprint:

  • Mam Tor is a high-end original television drama producer from the UK;
  • Beyond International8 is a leading Australian producer of media content with more than 8,000 hours of scripted and non-scripted in-house and third-party acquired English content across multiple territories and genres including factual entertainment, premium documentary and drama; and
  • MoviePlus Production an independent Israeli production company specializing in drama series, documentaries and feature-length films.

Pursuing the highest standards for responsible gaming

As part of its relentless commitment to ensuring the highest levels of player protection, Betclic ran a major responsible gaming education campaign in France in October 2022:

  • Educate players via the Betclic app as well as large-scale marketing campaign focused on playing with control
  • Increase public awareness to prevent underage gambling
  • Deepen the prevention of risky behavior with all the Betclic employees
  • Innovate with a safer gaming “lab sprint” made up of 100 Betclic experts including engineers, product managers and responsible gaming experts. Betclic also invests in the latest artificial intelligence technology to develop and improve its own algorithm for detecting behaviour patterns.

Betclic signed two partnerships with reference Associations:

  • E-Enfance, the first website for parents to help them prevent together their teenagers’ gambling
  • GamCare, a recognized expert in the prevention and treatment of gambling problems

FIRST 9M 2022 – PROFIT & LOSS STATEMENT

9M 2022 “Normalized P&L” highlights the underlying performance of the Group by removing the impact of one-off items related to reorganization and business combination (refer to page 9).

In € million 9M 2021 Reported 9M 2022 Reported 9M 2022 Normalized
P&L
% change
vs
9M 2021
Revenue 2 359.3 2 712.9 2 712.9 15.0%
External expenses (1 155.2) (1 308.5) (1 308.5)  
Personnel expenses excluding LTIP & employment-related earn-out & option expenses (815.9) (940.4) (940.4)  
Other operating income (loss) excl. restructuring costs & other non-recurring items (8.3) (15.8) (15.8)  
Depreciation and amortization expenses related to D&A fiction (0.1) (1.7) (1.7)  
Adjusted EBITDA 379.8 446.4 446.4 17.5%
Adjusted EBITDA margin 16.1% 16.5% 16.5%  
         
Restructuring costs and other non-recurring items (37.4) (99.5) 6.2  
LTIP & employment-related earn-out and option expenses (127.3) (104.7) (71.7)  
Depreciation and amortization (excl. D&A fiction) (81.3) (88.2) (88.2)  
Operating profit/(loss) 133.9 154.1 292.8 2.2x
         
Cost of net debt (99.5) (106.4) (106.4)  
Other finance income/(costs) (18.9) (81.1) 15.3  
Net financial income/(expense) (118.4) (187.5) (91.1) -23.1%
Share of net income from associates & joint ventures (1.3) (1.7) (1.7)  
Earnings before provision for income taxes 14.2 (35.1) 200.0 14.1x
         
Income tax expenses (16.0) (40.3) (40.3)  
Profit/(loss) from continuing operations (1.8) (75.4) 159.7  
Net income/(loss) for the period (1.8) (75.4) 159.7  
Attributable to:        
Non-controlling interests (4.8) 3.9 3.9  
Shareholders 3.0 (79.3) 155.8  
Restructuring costs and other non-recurring items 37.4 99.5 (6.2)  
LTIP & employment-related earn-out and option expenses 127.3 104.7 71.7  
Other finance income/(costs) 18.9 81.1 (15.3)  
Adjusted net income 181.8 209.8 209.8 15.4%

CONSOLIDATED REVENUE

Group revenue increased by +12.0% at constant exchange rates to €2,712.9m over the first 9M 2022, with robust growth of Content production & distribution business in particular. In absolute terms, consolidated revenue grew by +15.0% over the period (the difference mainly came from US$ and £ currencies).

The performance in 9M 2022 reflects, as expected, distinct growth pattern between first half and third quarter in the two business lines. This is attributable to the impact of covid lockdowns, a busier sports calendar in 2021 for Online sports betting & gaming, and a return to normalized pre-covid seasonality in Q3 2022 for Content Production & distribution.

This is reflected as follows by business:

In € million Q3 2021 Q3 2022 % change   9M 2021 9M 2022 % change % constant currency
Production 570.0 575.9 1.0%   1 499.4 1 744.2 16.3%  
Distribution 82.3 107.6 30.8%   192.8 267.2 38.6%  
Other 42.0 34.1 -18.7%   108.1 110.4 2.2%  
Content production & distribution 694.2 717.6 3.4%   1 800.2 2 121.8 17.9% 13.8%
                 
Sportsbook 111.8 154.8 38.5%   445.6 477.1 7.1%  
Casino 26.9 25.3 -5.7%   76.9 71.8 -6.5%  
Poker 10.5 11.7 11.4%   32.1 34.9 8.7%  
Other 1.4 2.6 87.1%   4.6 7.2 56.8%  
Online sports betting & gaming 150.4 194.4 29.3%   559.1 591.0 5.7% 5.8%
                 
TOTAL REVENUE 844.6 912.1 8.0%   2 359.3 2 712.9 15.0% 12.0%

Content production & distribution:

After a strong recovery in H1 2022 in comparison with H1 2021 that was still heavily impacted by Covid effects, the business returned to a normalized pre-covid seasonality pattern in Q3 2022. Revenue totaled €2,122m, up +17.9% in absolute terms and +13.8% at constant currency over the first 9M 2022.

Content production revenue rose by +16.3% over 9M 2022, driven by a dynamic production cycle, with the recommission of successful well-known programs (“Star Academy” and “Masterchef” in France), the development of new shows delivered for local and international markets across both non-scripted (“Blow-up” in Germany, Australia and New Zealand, “Starstruck” in the UK), and scripted (“SAS Rogue Heroes” for BBC in the UK and “Marie-Antoinette” for Canal+ in France) and to a lessor extent the positive impact from bolt-on acquisitions.

Distribution: revenue increased by +38.6% driven by both linear TV and streaming platforms for key non-scripted and scripted content such as “You” for Sky and “Peaky Blinders” for Netflix in the UK.

Overall, the number of content hours at the end of September 2022 reached about 146,000 hours9, up +25% versus 9M 2021.

Online sports betting & gaming:

The Online sports betting & gaming business recorded +5.7% revenue growth in absolute terms over the first 9M 2022 (+5.8% at constant currency) with a strong rebound in Q3 2022 (+29.3%) following a first half that saw a quieter sports calendar compared with H1 2021 (including the Euro 2020 football tournament held in June / July 2021). These figures also reflect the discontinued Bet-at-home activities.

At constant exchange rates and excluding discontinued Bet-at-home operations in certain jurisdictions, revenue was up +13% over 9M 2022, driven by the solid continued performance of Betclic entity (+15%), offsetting the -11% decline at Bet-at-home.

Unique Active Players increased sharply by +11% in 9M 2022 versus 9M 2021, illustrating the appeal of the Betclic platform.

ADJUSTED EBITDA

Adjusted EBITDA amounted to €446.4m, up +17.5% over 9M 2022, on revenue up +15.0%. This was driven by a strong +23.4% rise to €297.2m for Content production & distribution and +8.4% to €150.8m for Online sports betting & gaming.

Overall, this led to a 40bp improvement in Adjusted EBITDA margin to 16.5% for the first 9M 2022, with improved profitability across both business lines thanks to revenue growth and a higher proportion of Distribution revenue for Content production & distribution as well as a strong operational leverage for Online sports betting & gaming.

The increase in external and personnel expenses was mainly driven by Content production & distribution, in line with the increase in production revenue.

In € million   9M 2021 9M 2022 % change
         
Content production & distribution   240.8 297.2 23.4%
Online sports betting & gaming   139.1 150.8 8.4%
Holding   (0.1) (1.5)  
Adjusted EBITDA   379.8 446.4 17.5%
         
Content production & distribution   13.4% 14.0%  
Online sports betting & gaming   24.9% 25.5%  
Adjusted EBITDA margin   16.1% 16.5%  

NORMALIZED P&L: FROM ADJUSTED EBITDA TO ADJUSTED NET INCOME

Normalized P&L highlights the underlying performance of the group for the first 9M 2022 without one-off items related to reorganization and business combination.

Comments thereafter analyze the “Normalized P&L” over the first 9M 2022 compared to the first 9M 2021 reported P&L.

In € million 9M 2021 Reported 9M 2022 Reported (1) Transaction impact
(2)
9M 2022 Normalized P&L
(1) – (2)
Revenue 2 359.3 2 712.9   2 712.9
External expenses (1 155.2) (1 308.5)   (1 308.5)
Personnel expenses excluding LTIP & employment-related earn-out & option expenses (815.9) (940.4)   (940.4)
Other operating income (loss) excl. restructuring costs & other non-recurring items (8.3) (15.8)   (15.8)
Depreciation and amortization expenses related to D&A fiction (0.1) (1.7)   (1.7)
Adjusted EBITDA 379.8 446.4   446.4
Adjusted EBITDA margin 16.1% 16.5%   16.5%
         
Restructuring costs and other non-recurring items (37.4) (99.5) (105.7) 6.2
LTIP & employment-related earn-out and option expenses (127.3) (104.7) (33.0) (71.7)
Depreciation and amortization (excl. D&A fiction) (81.3) (88.2)   (88.2)
Operating profit/(loss) 133.9 154.1 (138.7) 292.8
         
Cost of net debt (99.5) (106.4) (106.4)
Other finance income/(costs) (18.9) (81.1) (96.4) 15.3
Net financial income/(expense) (118.4) (187.5) (96.4) (91.1)
Share of net income from associates & joint ventures (1.3) (1.7) (1.7)
Earnings before provision for income taxes 14.2 (35.1) (235.1) 200.0
         
Income tax expenses (16.0) (40.3) (40.3)
Profit/(loss) from continuing operations (1.8) (75.4) (235.1) 159.7
Net income/(loss) for the period (1.8) (75.4) (235.1) 159.7
Attributable to:        
Non-controlling interests (4.8) 3.9 3.9
Shareholders 3.0 (79.3) (235.1) 155.8
Restructuring costs and other non-recurring items 37.4 99.5 105.7 (6.2)
LTIP & employment-related earn-out and option expenses 127.3 104.7 33.0 71.7
Other financial income/(costs) 18.9 81.1 96.4 (15.3)
Adjusted net income 181.8 209.8 209.8

One-off items related to the transaction:

FL Entertainment recorded one-off items from the Group re-organization and listing transaction:

  • Restructuring and other non-recurring items: €106m related to listing and transaction fees and costs incurred to realize the transaction. Under IFRS, the merger with the SPAC is considered as an equity-settled share-based payment for a service rendered by the SPAC to list the Group. This service is valued at €86m and is recorded as a listing fee.
  • LTIP & employment-related earn-out and option expenses: €33m mainly driven by the change in fair value of financial instruments explained by the LTIP following the upward reassessment of the Banijay Group’s shares.
  • Other finance income / loss: €96m attributable mainly to the change in fair value of financial instruments. This includes re-evaluation and the change in fair value of Vivendi’s convertible bond derivatives following the upward assessment of the Banijay Group’s shares. This bond was paid back as part of the transaction.

Exceptional income from the deconsolidation of Bet-at-home Entertainment Ltd

FL Entertainment recorded a net exceptional income of +€6m mainly coming from the deconsolidation of Bet-at-home Entertainment Ltd in H1 2022.

Net financial result

Net financial result amounted to -€91.1m over 9M 2022 compared to -€118.4m in 9M 2021. Of this amount:

  • Cost of net debt totaled -€106.4m in 9M 2022 vs -€99.5m in 9M 2021, mostly attributable to a higher level of interest charges explained by a timing effect of interest charges related to Betclic loan issued on 13 December 2021.
  • Other financial income and expenses as of September 2022 amounted to +€15.3m, compared to – €18.9m for 9M 2021 mainly explained by derivatives during 9M 2022.

Income tax expenses

The tax charge in 9M 2022 totaled -€40.3m compared to -€16.0m in 9M 2021, representing an effective tax rate of 17.2% compared with 12.5% respectively.

The change is mostly explained by a particularly low effective income tax interest rate in over 9M 2021 due to the use of significant loss carry-forward in 2021 for Online sports betting & gaming business.

Adjusted net income

Adjusted net income rose by +15.3% to €209.8m in 9M 2022 from €181.8m in 9M 2021.

FREE CASH FLOW AND NET FINANCIAL DEBT OVER 9M 2022

FREE CASH FLOW CONVERSION

Adjusted free cash flow (after lease payments) reached €369m, up +66m yoy (+21.6%), driven by the business performance as well as a tight control of cash expenses and capex.

The change in working capital mainly derived from Content production and distribution. The third quarter traditionally has the highest requirements, reflecting the seasonality of the activity and the timing of deliveries.

The rise in income taxes paid was attributable to greater use of tax loss carry-forward in 9M 2021.

Adjusted free cash flow conversion after capex and leases payment amounted to 83%.

€m 9M 2021 9M 2022 % change
Adjusted EBITDA 379.8 446.4 17.5%
Capex (43.0) (43.2)  
Total cash outflows for leases that are not recognized as rental expenses (33.6) (34.3)  
Adjusted free-cash flow 303.3 368.9 21.6%
       
Change in working capital* (108.9) (101.1)  
Income tax paid (28.6) (48.6)  
Adjusted operating free cash flow 165.8 219.1 32.2%

*Excludes LTIP paid and exceptional items cash-out

SOLID FINANCIAL POSITION AND DE-LEVERAGING

The Group’s net financial debt as of September 30, 2022 stood at €2,272m, compared to €2,269m as of 31 December 2021. It is at fixed rate with no maturity before 2025.

The stability in net financial debt reflected the seasonality of the Content production & distribution business and negative exchange rates impact.

Net financial debt came mainly from an increase in adjusted free cash flows of the period for -€219m and cash proceeds received following the transaction (-€121m), partly offset by LTIP paid & exceptionals for €139m, net acquisitions for €68m and €106m interests recognized during
9M 2022.

The financial leverage ratio was 3.4x as of September 30, 2022, compared to 3.7x as of December 31, 2021.

Agenda

FY 2022 results: 16 March 2022

Investor Relations

Caroline Cohen – Phone: +33 1 44 95 23 34 – [email protected]

Press Relations

Anne-France Malrieu – [email protected]

About FL Entertainment

Founded by Stéphane Courbit, a 30-year entertainment industry pioneer and entrepreneur, FL Entertainment Group is a global leader in multimedia content and gambling, combining the strengths of Banijay, the world’s largest independent producer distributor, with Betclic Everest Group, the fastest-growing online sports betting platform in Europe. In 2021, FL Entertainment recorded through Banijay and Betclic Everest Group, a combined revenue, and adjusted EBITDA, of €3.5bn and €609m respectively. FL Entertainment listed on Euronext Amsterdam in July 2022.
ISIN: NL0015000X07 – Bloomberg: FLE NA – Reuters: FLE.AS

Forward-looking statements
This communication contains information that qualifies as inside information within the meaning of Article 7(1) of the EU Market Abuse Regulation.

Forward Looking Statements
Some statements in this press release may be considered “forward-looking statements”. By their nature, forward-looking statements involve risk and uncertainty because they relate to events and depend on circumstances that may occur in the future. These forward-looking statements involve known and unknown risks, uncertainties and other factors that are outside of our control and impossible to predict and may cause actual results to differ materially from any future results expressed or implied. These forward-looking statements are based on current expectations, estimates, forecasts, analyses and projections about the industry in which we operate and management’s beliefs and assumptions about possible future events. You are cautioned not to put undue reliance on these forward-looking statements, which only express views as at the date of this press release and are neither predictions nor guarantees of possible future events or circumstances.
We do not undertake any obligation to release publicly any revisions to these forward-looking statements to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events, except as may be required under applicable securities law.

Alternative performance measures
The financial information in this release includes non-IFRS financial measures and ratios (e.g. non-IFRS metrics, such as adjusted EBITDA) that are not recognized as measures of financial performance or liquidity under IFRS. The non-IFRS financial measures presented are measures used by management to monitor the underlying performance of the business and operations and, have therefore not been audited or reviewed. Furthermore, they may not be indicative of the historical operating results, nor are they meant to be predictive of future results. These non-IFRS measures are presented because they are considered important supplementary measurements of FL Entertainment N.V.’s (the “Company”) performance, and we believe that these and similar measures are widely used in the industry in which the Company operates as a way to evaluate a company’s operating performance and liquidity. Not all companies calculate non-IFRS financial measures in the same manner or on a consistent basis. As a result, these measures and ratios may not be comparable to measures used by other companies under the same or similar names. Further information on the non-IFRS measures can be found in our [reference to report].

Regulated information related to this press release is available on the website:
https://fl-entertainment.com/investor-relations/
https://fl-entertainment.com/

APPENDIX

Glossary

Transaction: business combination with Pegasus Entrepreneurial Acquisition Company Europe B.V., a special purpose acquisition company to become a listed company on Euronext Amsterdam as well as the Group’s re-organization

Adjusted EBITDA: for a period is defined as the Operating Profit for that period excluding restructuring costs and other non-core items, costs associated with the long-term incentive plan within the Group (the “LTIP”) and employment related earn-out and option expenses, and depreciation and amortization (excluding D&A fiction). D&A fiction are costs related to the amortization of fiction production, which the Group considers to be operating costs. As a result of the D&A fiction, the depreciation and amortization line item in the Group’s combined statement of income deviates from the depreciation and amortization costs in this line item.

Adjusted net income: defined as net income (loss) adjusted for restructuring costs and other non-core items, costs associated with the LTIP and employment related earn-out and option expenses and other financial income.

Adjusted free cash flow: defined as adjusted EBITDA adjusted for purchase and disposal of property plant and equipment and of intangible assets and cash outflows for leases that are not recognized as rental expenses.

Adjusted operating free cash flow: defined as adjusted EBITDA adjusted for purchase and disposal of property plant and equipment and of intangible assets, cash outflows for leases that are not recognized as rental expenses, change in WC, and income tax paid.

Net financial debt: defined as the sum of bonds, bank borrowings, bank overdrafts, vendor loans, accrued interests on bonds and bank borrowings minus cash and cash equivalents, trade receivables on providers, cash in trusts, plus players liabilities and escrow accounts plus (or minus) the fair value of net derivatives liabilities (or assets) for that period. Net financial debt is pre-IFRS 16.

Leverage: adjusted net financial debt / Adjusted EBITDA

Number of Unique Active Players: average number of unique players playing at least once a month in a defined period

Content production & distribution: Key indicators

Key indicators – In €m 9M 2021 9M 2022 % change % constant currency
Production 1 499.4 1 744.2 16.3%  
Distribution 192.8 267.2 38.6%  
Other 108.1 110.4 2.2%  
REVENUE 1 800.2 2 121.8 17.9% 13.8%
         
Adjusted EBITDA 240.8 297.2 23.4%  
Adjusted EBITDA margin (%) 13.4% 14.0%    
         
Capex (36.2) (36.8)    
Total cash outflows for leases that are not recognised as rental expenses (31.1) (31.7)    
         
Adjusted Free-cash flow 173.6 228.7 31.8%  
         
Change in WC* (92.7) (105.8)    
Income tax paid (17.7) (27.6)    
Adjusted Operating free cash flow 63.3 95.4 50.7%  

Online sports betting & gaming: Key indicators

Key indicators – €m 9M 2021 9M 2022 % change % constant currency
Sportsbook 445.6 477.1 7.1%  
Casino 76.9 71.8 -6.5%  
Poker 32.1 34.9 8.7%  
Other 4.6 7.2 56.8%  
REVENUE 559.1 591.0 5.7% 5.8%
         
Adjusted EBITDA 139.1 150.8 8.4%  
Adjusted EBITDA margin (%) 24.9% 25.5%    
         
Capex (6.8) (6.4)    
Total cash outflows for leases that are not recognised as rental expenses (2.6) (2.6)    
         
Adjusted free-cash flow 129.8 141.7 9.2%  
         
Change in WC* (16.2) 5.2    
Income tax paid (11.0) (21.0)    
Adjusted Operating free cash flow 102.6 125.9 22.6%  

*Excluding LTIP and exceptional items payment

Interim consolidated statement of cash flows

In € million 30 Sept. 2021 30 Sept. 2022
Profit/(loss) (1.9) (75.4)
Adjustments: 363.5 487.5
Share of profit/(loss) of associates and joint ventures 1.3 1.7
Amortization, depreciation, impairment losses and provisions, net of reversals 102.1 91.3
Employee benefits LTIP & employment-related earn-out and option expenses 127.3 104.7
Change in fair value of financial instruments 6.8 76.9
Income tax expenses 16.0 40.3
Other adjustments(1) 9.3 63.8
Share of profit/(loss) of associates and joint ventures 100.7 108.7
Gross cash provided by operating activities 361.6 412.1
Changes in working capital (164.8) (205.6)
Income tax paid (28.6) (48.6)
Net cash flows provided by operating activities 168.3 157.8
Purchase of property, plant and equipment and intangible assets (43.0) (43.2)
Purchases of consolidated companies, net of acquired cash (22.3) (36.3)
Increase in financial assets (3.4) (4.6)
Proceeds from sales of consolidated companies, after divested cash 7.5 3.8
Decrease in financial assets 0.5 163.5
Net cash provided by/(used for) investing activities (60.7) 83.2
Change in capital   364.8
Change in other securities   114.4
Dividends paid (30.0) (0.2)
Dividends paid by consolidated companies to their non-controlling interests (43.2) (3.6)
Transactions with non-controlling interests (2.1) (3.4)
Proceeds from borrowings and other financial liabilities 23.5 15.6
Repayment of borrowings and other financial liabilities (51.1) (365.7)
Repayment of vendor loans   (388.5)
Other cash items related to financial activities (0.8) (0.1)
Interest paid (106.9) (111.1)
Net cash flows from/(used in) financing activities (210.7) (377.7)
Impact of changes in foreign exchange rates (9.9) 36.7
Net increase/(decrease) of cash and cash equivalents (113.0) (100.1)
     
Cash and cash equivalents at the beginning of the period 388.5 432.4
Cash and cash equivalents at end of the period 275.5 332.4

(1) Other adjustments include notably unrealized foreign exchange gains on disposal and liquidation of subsidiaries

Interim consolidated statement of financial position

In € million 31-Dec-2021 30-Sep-2022
ASSETS    
Goodwill 2 493.9 2 557.3
Intangible assets 236.7 219.6
Right-of-use assets 171.1 155.1
Property, plant and equipment 55.3 59.3
Investments in associates and joint ventures 11.1 12.6
Non-current financial assets 83.0 131.3
Other non-current assets 29.6 20.6
Deferred tax assets 47.6 27.1
Non-current assets 3 128.3 3 182.9
Inventories and work in progress 676.7 882.7
Trade receivables 463.6 518.8
Other current assets 264.2 324.0
Current financial assets 75.2 36.3
Cash and cash equivalents 434.1 335.8
Current assets 1 913.7 2 097.6
TOTAL ASSETS 5 042.0 5 280.5
     
EQUITY AND LIABILITIES    
Share capital 8.0
Share premium and retained earnings 73.6 47.8
Net income/(loss) – attributable to shareholders (43.0) (79.3)
Shareholders’ equity 30.6 (23.5)
Non-controlling interests (36.7) 0.7
Total equity (6.2) (22.8)
     
Other securities 135.7
Long-term borrowings and other financial liabilities 2 457.8 2 535.5
Long-term lease liabilities 143.2 124.5
Non-current provisions 22.0 23.8
Other non-current liabilities 291.7 391.5
Deferred tax liabilities 3.2 9.4
Non-current liabilities 2 917.9 3 220.5
     
Short-term borrowings and bank overdrafts 306.2 158.2
Short-term lease liabilities 40.2 41.9
Trade payables 511.2 558.6
Current provisions 39.1 12.5
Customer contract liabilities 776.9 912.3
Other current liabilities 456.8 399.4
Current liabilities 2 130.3 2 082.9
TOTAL EQUITY AND LIABILITIES 5 042.0 5 280.5

IFRS consolidated net financial debt

In € million 31-Dec-2021 30-Sep-2022
Bonds 1 461.5 1 362.6
Bank borrowings 1 232.5 1 176.3
Bank overdrafts 1.7 3.4
Accrued interests on bonds and bank borrowings 32.7 14.3
Vendor loans 137.2
Total bank indebtedness 2 728.4 2 693.8
Cash and cash equivalents (434.1) (335.8)
Trade receivables on providers (24.8) (10.2)
Players’ liabilities 41.7 40.8
Cash in trusts (22.4) (22.0)
Net cash and cash equivalents (439.5) (327.1)
     
Net debt before derivatives effects 2 288.8 2 366.7
Derivatives – liabilities 6.1
Derivatives – assets (26.2) (94.8)
Net debt 2 268.8 2 271.8

Content production & distribution: net financial debt as at 30 September 2022

Net financial debt – In €m 31Dec2021 31Mar2022 30Jun2022 30Sep2022
At Banijay level:        
Total Secured Debt (OM definition) 1 805 1 809 1 871 1 914
         
Other debt 296 279 313 314
SUN 409 402 409 402
Total Debt 2 510 2 490 2 593 2 630
Available financial assets       (78)
Net Cash (342) (312) (353) (230)
Total net financial debt 2 168 2 178 2 240 2 322
         
EO & PUT 100 114 116 115
Total net financial debt (incl EO & PUT) 2 268 2 292 2 355 2 437
         
At FL Entertainment level:        
Transaction costs amortization     (48) (44)
Lease debt (IFRS 16)     (156) (155)
Total net financial debt at FL Entertainment level  2 035 2 122
         
Derivatives     (49) (90)
Total net financial debt at FL Entertainment level 1 987 2 032
         
Ratios at Banijay level:        
Leverage Ratio, as presented 4.85 4.66 4.60 4.55
Adjusted Leverage Ratio, as presented 5.07 4.91 4.84 4.78
Senior secured net leverage ratio 3.50 3.45 3.35 3.37

1 Adjusted EBITDA and adjusted free cash flow: refer to the Appendix for definition
2 Net debt: pre-IFRS 16
3 At constant exchange rates
4 2022 YTD
5 Excluding discontinued operations at Bet-at-home
6 Content production & distribution
7 Of which one acquisition is signed, not yet completed
8 Acquisition signed, not yet realized
9 Including all the bolt-on acquisitions signed and/or completed

Attachment

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Artificial Intelligence

The Australia Data Center Market Size Will Witness Investments of $7.71 Billion by 2029 – Get Insights on 135 Existing Data Centers and 23 Upcoming Facilities across Australia – Arizton

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CHICAGO, May 9, 2024 /PRNewswire/ — According to Arizton’s latest research report, the Australia data center market is growing at a CAGR of 3.22% during 2023-2029.

To Know More, Click: https://www.arizton.com/market-reports/australia-data-center-market-investment-analysis
Australia Data Center Market Report Scope
Report Attributes
Details
Market Size (Investment)
USD 7.71 Billion (2029)
Market Size (Area)
1,460.0 thousand sq. Feet (2029)
Market Size (Power Capacity)
303.0 MW (2029)
CAGR Investment (2023-2029)
3.22 %
Colocation Market Size (Revenue)
USD 2.05 Billion (2029)
Historic Year
2020-2022
Base Year
2023
Forecast Year
2024-2029
The data center market in Australia has been witnessing significant growth in investments over the past few years. It is expected to grow at an absolute growth rate of around 20% between 2023-2029. Australia is among the top destinations for data center investments in the APAC region.
Sydney, Melbourne, and Perth are the primary data center hubs hosting most data centers in the country. Canberra, Brisbane, Darwin, and other cities are among the emerging locations in Australia with abundant land availability for data center development.
Investment Opportunities
In November 2023, OVHcloud announced the launch of its upcoming SYD3 Sydney data center facility, which is expected to be operational in 2024.In November of 2023, Rest Super invested about $656 million in a data center in Brisbane, which Quinbrook Infrastructure Partners are developing.In November 2023, NEXTDC announced the development of the D1 data center facility in Darwin; the facility is expected to go operational by Q2 2024.AirTrunk announced the expansion of its SYD2 data center campus in Sydney; once fully built, the facility will account for an additional power capacity of around 30 MW, making it an aggregate capacity of around 120 MW. This second phase is expected to be completed in 2024. AirTrunk’s upcoming SYD3 Sydney facility calls for an aggregate investment of about $670 million.In an August 2023 news article, Macquarie Data Centres revealed its plan to expand its upcoming IC3 Super West facility in Sydney regarding power capacity. As per January 2024 news article, Macquarie Data Centres has received approval to build/grow the IC3 Super West, its third facility in Sydney.In August 2023, STACK Infrastructure announced the MEL01 A data center launch in Melbourne, located at 399 Palmers Road. The entire campus will have a power capacity of around 72 MW, divided equally between buildings A and B. As of early 2024, Building B is still a work in progress. Furthermore, the company plans new facilities in Canberra, Hume, and Perth.Rising Procurement of Renewable Energy in Australia Boosting the Market Opportunities
In 2022, according to IRENA, solar energy accounted for around 61% of Australia’s overall renewable energy capacity, followed by wind, hydro, and bioenergy (in decreasing order), from which renewable power is extracted for all the sustainable energy needs of the country. Australia aims to achieve its target of zero carbon emissions by 2050. The country announced plans to reach almost 43% less emission than in 2005.
According to the Australia National Electricity Market (NEM), the renewable energy share in the country is expected to reach around 41% by 2030. By 2025, Australia aims to achieve 100% instantaneous renewable energy for its main grid, starting with a half-hour period and gradually increasing to cover hours and days. This transition will be facilitated by an increase in wind, solar, and energy storage solutions to meet the country’s new target of 82% renewables by 2030. The retirement of coal-based power generation facilities in the coming years will contribute to this goal.
Microsoft in Australia Recent Development During 2022-2024:
In October 2023, Microsoft, a hyperscale tech giant, decided to expand its footprint in Australia by investing over $3 billion to increase and expand its computing capacity in the country by over 250% in the next two years. It is expected to go live by late 2025.In July 2023, Microsoft announced the completion of the construction of Building 1 of the Station Road data center; Building 2 is still a work in progress. This is expected to be completed by late 2024.Why Should You Buy This Research? 
Market size is available in terms of investment, area, power capacity, and Australia colocation market revenue.An assessment of the data center investment in Australia by colocation, hyperscale, and enterprise operators.Investments in the area (square feet) and power capacity (MW) across cities in the country.A detailed study of the existing Australia data center market landscape, an in-depth market analysis, and insightful predictions about market size during the forecast period.Snapshot of existing and upcoming third-party data center facilities in AustraliaFacilities Covered (Existing): 135Facilities Identified (Upcoming): 23Coverage: 20 LocationsExisting vs. Upcoming (Area)Existing vs. Upcoming (IT Load Capacity)Data Center Colocation Market in the AustraliaColocation Market Revenue & Forecast (2023-2029)Retail Colocation Revenue (2023-2029)Retail Colocation PricingThe Australia data center market investments are classified into IT, power, cooling, and general construction services with sizing and forecast.A comprehensive analysis of the latest trends, growth rate, potential opportunities, growth restraints, and prospects for the industry.Business overview and product offerings of prominent IT infrastructure providers, construction contractors, support infrastructure providers, and investors operating in the market.A transparent research methodology and the analysis of the demand and supply aspects of the market.Market Segmentation
IT InfrastructureServersStorage SystemsNetwork InfrastructureElectrical InfrastructureUPS SystemsGeneratorsSwitches & SwitchgearsPDUsOther Electrical InfrastructureMechanical InfrastructureCooling SystemsRack CabinetsOther Mechanical InfrastructureCooling SystemsCRAC and CRAHChillersCooling Towers, Condensers and Dry CoolersEconomizers and Evaporative CoolersOther Cooling UnitsGeneral ConstructionCore & Shell DevelopmentInstallation & commissioning ServicesBuilding & Engineering DesignFire Detection & Suppression SystemsPhysical SecurityData Center Infrastructure Management (DCIM)Tier StandardTier I & Tier IITier IIITier IVGeographySydneyMelbournePerthOther CitiesVendor Landscape
IT Infrastructure Providers: Arista Networks, Atos, Broadcom, Cisco Systems, Dell Technologies, Extreme Networks, Hewlett Packard Enterprise, Hitachi Vintara, IBM, Juniper Networks, Lenovo, Oracle, Pure Storage, Quanta Cloud Technology, and Super Micro Computer.Data Center Construction Contractors & Sub-Contractors: AECOM, A W Edwards, Aurecon, Benmax, BGIS, Dem, FDC Construction & Fitout, FKG Group, Greenbox Architecture, HDR (Hurley Palmer Flatt), Hutchinson Builders, Icon, ISG, John Holland, Kapitol Group, Linesight, Manteena Group, Nilsen, Paramount Airconditioning, Parratech, SCEE Group, Stowe Australia, & Taylor Group Construction.Support Infrastructure Providers: ABB, Airedale, Alfa Laval, Canovate, Caterpillar, Condair, Cummins, Delta Electronics, Eaton, Everett Smith & Co, Green Revolution Cooling, HITEC Power Protection, Kohler, Legrand, Mitsubishi Electric, Piller Power Systems, Rittal, Rolls Royce, Schneider Electric, STULZ, Thycon, & Vertiv.Data Center Investors: 5G Networks, AirTrunk, Amazon Web Services, CDC Data Centres, DC Two, DCI Data Centers, Digital Realty, Equinix, Edge Centres, Fujitsu, Global Switch, Leading Edge Data Centres, Keppel Data Centres, Macquarie Data Centres, Microsoft, NEXTDC, & STACK Infrastructure.New Entrants: GreenSquareDC, Stockland, Supernode, Trifalga, & Vantage Data Centers.Key Questions Answered in the Report:
Q: How big is the Australia data center market?
Q: How much MW of power capacity will be added across Australia from 2024 to 2029?
Q: What is the growth rate of the Australia data center market?
Q: What factors are driving the Australia data center market?
Q: Which cities are included in the Australia data center market report?
Get the Detailed TOC @ https://www.arizton.com/market-reports/australia-data-center-market-investment-analysis
Check Out Some of the Top Selling Research Reports:    
Singapore Data Center Market – Investment Analysis & Growth Opportunities 2024-2029
South Korea Data Center Market – Investment Analysis & Growth Opportunities 2024-2029
Indonesia Data Center Market – Investment Analysis & Growth Opportunities 2024-2029
Taiwan Data Center Market – Investment Analysis & Growth Opportunities 2024-2029
Why Arizton?                 
100% Customer Satisfaction                 
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80% of our reports are exclusive and first in the industry                 
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1500+ reports published till date                  
About Us:                                                      
Arizton Advisory and Intelligence is an innovative and quality-driven firm that offers cutting-edge research solutions to clients worldwide. We excel in providing comprehensive market intelligence reports and advisory and consulting services.                                                    
We offer comprehensive market research reports on consumer goods & retail technology, automotive and mobility, smart tech, healthcare, life sciences, industrial machinery, chemicals, materials, I.T. and media, logistics, and packaging. These reports contain detailed industry analysis, market size, share, growth drivers, and trend forecasts.                                                     
Arizton comprises a team of exuberant and well-experienced analysts who have mastered generating incisive reports. Our specialist analysts possess exemplary skills in market research. We train our team in advanced research practices, techniques, and ethics to outperform in fabricating impregnable research reports.                                                           
Contact Us                                                   Call: +1-312-235-2040                                                            +1 302 469 0707                                                 Mail: [email protected]                                                   Contact Us: https://www.arizton.com/contact-us                                                   Blog: https://www.arizton.com/blog                                                   Website: https://www.arizton.com/
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Invoca Named a Leader in Real-Time Revenue Execution Platforms Report

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Report recognises Invoca’s innovative platform for delivering “game-changing AI capabilities to revenue teams.”
SANTA BARBARA, Calif., May 9, 2024 /PRNewswire/ — Invoca today announced that Forrester Research has named Invoca as a Leader in The Forrester Wave™: Real-Time Revenue Execution Platforms, Q2 2024 report. Forrester evaluated the most significant revenue execution platform vendors based on three main categories — current offering, strategy, and market presence — along with interviews with customers. Invoca is the top-ranked vendor in both the current offering and strategy categories and among the top-ranked in market presence. Invoca also received the highest possible score in 19 of the 31 evaluation criteria, including AI differentiators, AI: large language model utilisation, Marketing: performance optimisation, In-call guidance: pre-call insights, System configuration: privacy, and Interaction capture: integrations.

The report states, “[Invoca’s] success starts with a vision focused on enabling revenue teams to drive growth by delivering the most complete platform for optimising the entire buying experience. Invoca has a track record of innovation that continues to raise the bar on what is possible to fulfil its vision.”
Revenue Execution Platforms Unify the Buying Journey to Drive Revenue Growth
Invoca’s revenue execution platform enables revenue teams to connect customer buying journey data across the marketing team that engages customers and the sales teams that close the deals. By using a comprehensive revenue execution platform, revenue teams can finally connect their marketing investments directly to revenue, improve digital engagement, and drive higher-quality leads.
Invoca also enables sales teams in the contact centre or at distributed business locations to access information from the customer’s digital journey from a centralised source, enabling them to provide the best call experience possible and close more sales opportunities.
Revenue Execution Platforms Needed to Power Today’s Buyer Journey
“B2C revenue teams across marketing and sales are feeling more pressure to directly connect revenue to their investments. But a lack of alignment and poor visibility of the full buying journey makes that nearly impossible,” said Peter Isaacson, Chief Marketing Officer at Invoca. “I believe Invoca was named a revenue execution Leader because we help marketing and sales teams manage the complete buyer journey from the first click to the final sale, so they can drive revenue growth.”
By using Invoca’s comprehensive revenue execution platform, revenue teams can connect their paid media investments directly to revenue, improve digital engagement and deliver the best buyer experiences to drive more sales. The Forrester report states that “reference customers rave about the versatility of the platform and its collaboration with customers around enhancements.”
Windstream, an Invoca customer, embodies this approach to revenue execution by tightly aligning the marketing and sales teams so they can work together to increase revenue.
“‍We’re a better marketing organisation because we have a strong partnership with sales,” said Aaron Pierce, VP of Marketing at Windstream. “Our teams have realised that we make each other better — I think that’s the biggest win. And now, when we have a problem, we can put all the smartest people together in the room to tackle it.”
“The Invoca platform has allowed us to unlock a ‘full-funnel’ view of our marketing performance that incorporates both online and offline,” said Lorenzo Clark, VP of Digital Sales at Windstream. “Now, we can get a read on lead quality because we can see what’s happening on sales calls and also track sales performance on a lead-by-lead basis.”
The Forrester Wave™The Forrester Wave™ is Forrester’s evaluation of top products in a technology market. The report assesses the core capabilities and strategies of these products based on an executive strategy briefing and/or product demo session, criteria questionnaire, and customer reference calls/surveys.
The Forrester Wave™: Real-Time Revenue Execution Platforms, Q2 2024 report is available for download here.
Additional Resources:
Learn more about Revenue Execution Platforms: https://www.invoca.com/uk/product/revenue-execution-platformHow real-time revenue execution platforms drive business growth: https://www.invoca.com/uk/blog/revenue-execution-platformThe 5 Revenue Execution Platform Uses You Need to Know About: https://www.invoca.com/uk/blog/revenue-execution-platform-usesAbout InvocaInvoca is the leading revenue execution platform to connect marketing and sales teams to enable them to track and optimise the buying journey and drive more revenue. By using a comprehensive revenue execution platform with deep integrations with leading technology platforms, revenue teams can better connect their paid media investments directly to revenue, improve digital engagement, and deliver the best buyer experiences to drive more sales. With Invoca, top consumer brands, including AutoNation, DIRECTV, Mayo Clinic, Mutual of Omaha, and Verizon, experience unbelievable results powered by undeniable data. Invoca has raised $184M from leading venture capitalists, including Upfront Ventures, Accel, Silver Lake Waterman, H.I.G. Growth Partners, and Salesforce Ventures. For more information, visit www.invoca.com.
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Fight Against Pancreatic Cancer Ramps Up as Market Size Revenues Expected to Exceed $36 Billion by 2036

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FN Media Group News Commentary
PALM BEACH, Fla., May 9, 2024 /PRNewswire/ — The incidence of pancreatic cancer is increasing globally, which is driving the growth of the market. As of 2023, the American Cancer Society predicts that 64,050 Americans will be diagnosed with pancreatic cancer. It is estimated that 50,550 people will die from pancreatic cancer (26,620 men and 23,930 women). Pancreatic cancer is an aggressive form of cancer, and it is often not detected until it is in an advanced stage. Additionally, the treatment options for pancreatic cancer are limited, and the survival rate is low. These factors are contributing to the rise in pancreatic cancer cases, which in turn is driving the growth of the pancreatic cancer market.  A recent report from Research Nester projected that the global pancreatic cancer market size is slated to expand at ~18% CAGR between 2024 and 2036. The market is poised to garner a revenue of USD 36 billion by the end of 2036, up from a revenue of ~USD 6 billion in the year 2023. The report said: “Advancements in diagnosis and treatment options for pancreatic cancer are also driving the growth of the market. As researchers gain a better understanding of the different types of pancreatic cancer, they are developing more targeted treatments that are more likely to be effective with fewer side effects. Additionally, new treatment options, such as immunotherapy and targeted therapies, are improving patient outcomes and extending survival rates.”  Active biotech and pharma companies in the markets this week include Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), Zai Lab Limited (NASDAQ: ZLAB), Notable Labs, Ltd. (NASDAQ: NTBL), Cardiff Oncology, Inc. (NASDAQ: CRDF), Johnson & Johnson (NYSE: JNJ).

Research Nester concluded: “The pancreatic cancer market in North America is garner the largest revenue by the end of 2036 due to several demographic changes, including an aging population and increased incidence of obesity and diabetes. In the US, there are 37.3 million diabetics (11.3[R3] % of the population); 28.7 million are diagnosed with diabetes, including 28.5 million adults. As the population ages, there will be a higher prevalence of chronic diseases such as diabetes and obesity, which are risk factors for pancreatic cancer. Additionally, the aging population will lead to an increase in the number of people with pre-existing conditions that can increase the risk of developing pancreatic cancer. Obesity and diabetes are known risk factors for pancreatic cancer, and as these conditions become more prevalent, the number of cases of pancreatic cancer is expected to increase.”
Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC) Receives Regulatory Clearance to Evaluate Pelareorep in Combination with Modified FOLFIRINOX +/- an anti-PD-L1 Inhibitor in Pancreatic Cancer 
US$5 million PanCAN grant provides important support for the fifth cohort of the GOBLET study  Study of modified OLFIRINOX/pelareorep/atezolizumab (Tecentriq ®) combination expands existing pancreatic cancer program  First patient expected to be enrolled in Q2 2024 Oncolytics Biotech ® Inc., a leading clinical-stage company specializing in immunotherapy for oncology, will commence enrollment into a new GOBLET study pancreatic cancer cohort following both German regulatory and ethics approvals. This cohort will evaluate pelareorep in combination with modified FOLFIRINOX (mFOLFIRINOX) with or without the PD-L1 immune checkpoint inhibitor atezolizumab (Tecentriq ® ) in newly diagnosed patients with pancreatic ductal adenocarcinoma (PDAC). It is supported by a US$5M Therapeutic Accelerator Award from the Pancreatic Cancer Action Network (PanCAN), an innovative program established to accelerate the development of new treatments for pancreatic cancer. The chemotherapy regimens of mFOLFIRINOX or gemcitabine + nab-paclitaxel are the two most common standards of care for pancreatic cancer.  Oncolytics has already reported data with the combination of gemcitabine and nab-paclitaxel ( link to the PR , link to the poster ) that surpassed historical outcomes. Positive results from a combination with mFOLFIRINOX could greatly enhance pelareorep’s potential in addressing pancreatic cancer.
“Oncolytics is pleased to announce receipt of regulatory clearance to initiate the mFOLFIRINOX cohort in patients with newly diagnosed metastatic PDAC. We appreciate the opportunity to collaborate with PanCAN, Roche, and AIO on this cohort, which is expected to initiate enrollment in the second quarter,” said Dr. Matt Coffey, President and Chief Executive Officer of Oncolytics. “We believe that working with PanCAN will help to further enrich Oncolytics’ clinical relationships with the pancreatic cancer community. We are also grateful for PanCAN’s Therapeutic Accelerator Award, which is enabling the evaluation of this combination therapy.”
“The Therapeutic Accelerator Award program has been an important part of PanCAN’s approach to advancing innovative treatments for pancreatic cancer. We incorporated input from leading scientists and clinicians in the field of pancreatic cancer to select Oncolytics as a recipient of this award,” said Anna Berkenblit , MD, MMSc, Chief Scientific and Medical Officer at PanCAN. “Increasing patient access to clinical trials is vital to developing improved treatment options, so we are pleased that Oncolytics has received regulatory clearance for the pelareorep/mFOLFIRINOX combination and is poised to enroll the first patient in this cohort. We hope that the results from this study lead to improved outcomes for patients with pancreatic cancer.”
Dirk Arnold , M.D., Ph.D., Director of Asklepios Tumorzentrum Hamburg and primary investigator of the GOBLET trial, commented, “Oncolytics has taken a very strategic approach to the development of pelareorep in pancreatic cancer by focusing its clinical studies on combinations with the most widely used treatment regimens. My experience to date with the GOBLET study, including the positive metastatic PDAC and encouraging anal cancer data reported last year, makes me enthusiastic to initiate enrollment in the mFOLFIRINOX cohort.”
“We previously reported very encouraging results in pancreatic cancer patients for the combination of pelareorep, gemcitabine/nab-paclitaxel, and atezolizumab, and we plan to begin a registration-enabling study of this regimen later this year. The new pelareorep/mFOLFIRINOX cohort offers the opportunity to expand pelareorep’s role in pancreatic cancer. If the mFOLFIRINOX combination shows a compelling efficacy signal, this therapeutic approach could also be advanced to a registration-enabling study, providing two opportunities for pelareorep-based treatment to benefit pancreatic cancer patients,” said Thomas Heineman , M.D., Ph.D., Chief Medical Officer at Oncolytics. “In addition, translational research studies planned for this cohort will help to further elucidate pelareorep’s mechanism of action, including its ability to shape the tumor microenvironment (TME). Notably, we will evaluate the correlation between tumor responses and the expansion of tumor-infiltrating lymphocytes (TILs) in the blood, an effect that was observed in earlier pancreatic cancer studies. We look forward to initiating enrollment into the mFOLFIRINOX/pelareorep study cohort in the second quarter of this year.” CONTINUED… Read these full press releases and more news for ONCY at: https://www.financialnewsmedia.com/news-oncy/  
Other recent developments in the biotech industry of note for cancer events include:
Zai Lab Limited (NASDAQ: ZLAB) recently announced financial results for the first quarter of 2024, along with recent product highlights and corporate updates. “Our first quarter results demonstrate strong commercial execution and pipeline progress across our potential first- and best-in-class product portfolio,” said Dr. Samantha Du, Founder, Chairperson, and Chief Executive Officer of Zai Lab. “The launch of VYVGART is off to an impressive start with $13.2 million of sales in the first quarter. Looking ahead, we expect to accelerate commercial performance for the remainder of the year and are preparing for three new potential launches in 2024. We are also excited by the progress of our late-stage pipeline and we are on track to achieve the objectives outlined in our five-year strategic plan, including significant revenue growth and profitability by the end of 2025.”
“Our net revenues grew 39% y-o-y or 43% y-o-y at CER in the first quarter, driven by strong execution with the launch of VYVGART and uptake of our existing portfolio,” said Josh Smiley, President and Chief Operating Officer of Zai Lab. “With VYVGART’s launch in gMG at the end of last year, and multiple new products and indications expected to launch over the near-term, we are now entering a period of robust growth for Zai Lab. Our significant growth, coupled with our focus on driving efficiencies and productivity across the organization, will drive the evolution of Zai Lab into a profitable, high growth business by the end of 2025. Furthermore, we will continue to focus on expanding our global portfolio through our internal discovery activities and strategic business development,” Mr. Smiley concluded.
Notable Labs, Ltd. (NASDAQ: NTBL), a clinical-stage precision oncology company developing new cancer therapies identified by its Predictive Precision Medicine Platform (PPMP), recently reported financial results for the year ended December 31, 2023 and provided a business update.
“The last year has been a time of great accomplishment for Notable. We built a strong clinical validation dataset, starting with a poster presented at the American Association for Cancer Research (AACR 2023); became a publicly listed company, following the closing of a reverse merger in October 2023; and reported successful PPMP clinical data from the Phase 2 fosciclopirox study that showcased the ability of our platform to accurately predict patient outcomes for specific therapeutics,” said Thomas Bock, M.D., Chief Executive Officer of Notable. “The performance of our platform in accurately predicting the outcome of the fosciclopirox study has enabled us to enhance the clinical trial plan for our lead product candidate, volasertib, in development for patients with relapsed/refractory acute myeloid leukemia (r/r AML). In our upcoming Phase 2 trial, we will be utilizing the platform to enrich the study’s enrollment with patients predicted to respond to volasertib, which we believe will result in more rapid enrollment, shorter time to efficacy data and, ultimately, increased probability of success.”
Cardiff Oncology, Inc. (NASDAQ: CRDF), a clinical-stage biotechnology company leveraging PLK1 inhibition to develop novel therapies across a range of cancers, recently announced financial results for the first quarter ended March 31, 2024, and provided a business update.
“During the start of 2024, we presented several important new data sets supporting our first-line RAS-mutated mCRC strategy and the broader opportunity for onvansertib,” said Mark Erlander, Ph.D., Chief Executive Officer of Cardiff Oncology. “The data from the ONSEMBLE trial replicated, in a second independent and randomized dataset, the bev naïve signal from our earlier Phase 1b/2 KRAS-mutated mCRC trial. And the Phase 1b data published in the peer-reviewed journal Clinical Cancer Research, and the additional data we presented in one of our five posters at AACR, further substantiated our lead program in RAS-mutated mCRC. The additional AACR posters also point toward new indications for onvansertib in RAS wild-type mCRC, small cell lung cancer and ovarian cancer. Looking ahead, we believe that our upcoming data readout from our first-line trial in RAS-mutated mCRC has the potential to serve as a key value inflection point for our company and revolutionize the treatment of RAS-mutated mCRC, an area with no new treatments approved in over two decades.”
Johnson & Johnson (NYSE: JNJ) recently announced that the U.S. Food and Drug Administration (FDA) has approved CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least one prior line of therapy, including a proteasome inhibitor and an immunomodulatory agent, and are refractory to lenalidomide. With this approval, CARVYKTI® becomes the first and only B-cell maturation antigen (BCMA)-targeted therapy approved for the treatment of patients with multiple myeloma as early as first relapse.
FDA approval is based on positive results from the Phase 3 CARTITUDE-4 study, which demonstrated that the earlier use of CARVYKTI® reduced the risk of disease progression or death by 59 percent compared to standard therapies—pomalidomide, bortezomib and dexamethasone (PVd) or daratumumab, pomalidomide and dexamethasone (DPd)—in adults with relapsed and lenalidomide-refractory multiple myeloma who received one to three prior lines of therapy. The study, which was presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting and published in The New England Journal of Medicine, also included and reported key secondary results such as overall response (OR) and overall survival (OS).
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