Artificial Intelligence
Sema4 Announces Nationwide Expansion of Disparity Study to Deliver Precision Oncology Care to Underserved Communities
– The REPRESENT Study Will Create One of the Most Diverse and Comprehensive Clinico-genomic Datasets to Uncover and Address Disparities in Cancer Care
– Sema4’s Chief Medical Science Officer Will Discuss the Study at the Community Oncology Alliance’s Annual Conference
STAMFORD, Conn., March 16, 2022 (GLOBE NEWSWIRE) — Sema4 (NYSE: SMFR), a patient-centered artificial intelligence (AI)-driven genomic and clinical data platform company, today announced the nationwide expansion of its disparities in cancer care study. The study, launched in 2021, enables access to comprehensive genetic and genomic testing for advanced cancer patients in underserved communities. It will also create one of the most diverse clinical-genomic datasets to help resolve racial, ethnic, and socioeconomic disparities in clinical trials, research, and therapeutics. William Oh, MD, Chief Medical Science Officer at Sema4, will discuss the study at the Community Oncology Alliance’s upcoming conference in Florida on March 18th.
The REsearch to advance PREciSion medicine and health Equity in oNcology Treatment (REPRESENT) study, which is already enrolling patients at five locations across two sites, will run nationally in collaboration with community oncologists caring for patients with advanced cancer in diverse and traditionally understudied and underserved populations. Disparities in healthcare access and a lack of diversity in clinical trials have led to significant disparities in the standard of oncology care. For example, Black and African American individuals have higher mortality rates than all other racial and ethnic groups for many cancer types. Sema4’s study aims to better understand the factors contributing to cancer care disparities in underserved populations, including socioeconomic and genetic considerations, by creating a diverse and comprehensive patient registry and biobank.
“Sema4 is committed to partnering with community-based oncologists to democratize access to somatic and germline testing in underserved communities,” said Eric Schadt, PhD, Founder and Chief Executive Officer, Sema4. “We aim to break the cycle of inequity whereby underserved communities do not have access to precision oncology testing, and thus experience poorer outcomes, and are often excluded from clinical trials, research, and approved therapeutics. The question underlying the REPRESENT study is whether increased uptake of precision oncology testing in underserved populations will reduce disparities in health outcomes. The first step to answering this question is to create a dataset and biobank that reflect the United States’ true diversity.”
Most information in current clinical-genomic datasets comes from patients of European descent. Similarly, many clinical trials are underrepresented by certain racial and ethnic groups, limiting understanding of drug efficacy and toxicity in certain populations. As a result, many drugs and treatment plans are designed around information from the European population, further contributing to disparities in cancer care and outcomes for underserved groups.
Sema4 aims to uncover insights into cancer biology and treatment relevant to these underserved populations by recruiting and offering advanced genomic testing to diverse patient populations. This information may open up new genetically tailored treatment options for participating patients in the immediate term. In the longer term, this information will be used to guide future drug development and clinical trials for underserved populations, potentially leading to better health outcomes.
“This is an unprecedented era in novel cancer therapies, but, unfortunately, precision oncology treatment is not delivered uniformly to all patients,” said William Oh, MD, Chief Medical Science Officer, Sema4. “By better understanding the genomic landscape of cancer in underserved populations, we hope to enable personalized care and uncover treatment patterns within these communities and ensure patient diversity in the development of cancer research, trials, and therapeutics.”
REPRESENT is a prospective observational study that will enroll up to 5,000 advanced-stage cancer patients (up to 500 at each of a maximum of ten national trial sites). Two sites are currently operating in North and South Carolina, with 226 patients enrolled, and nine other sites are in discussion. As part of the study’s criteria, at least 30% of enrolled patients at each site must be part of an underserved minority community. Data and samples gathered from consenting patients will be used to establish a clinical-genomic patient registry and biobank. Registries are used to collect standardized patient information. Similarly, biobanks, which are essential resources in the development of targeted therapies in oncology, contain clinical data, biological specimens, and additional associated information for future use in research and clinical testing.
“The REPRESENT study will generate one of the most comprehensive repositories of clinical-genomic information available as a result of the range of molecular profiling techniques, clinical data, and diverse racial backgrounds involved,” said Kashyap Patel, MD, President of the Community Oncology Alliance and CEO of the Carolina Blood and Cancer Care and study co-principal investigator. “Furthermore, by incorporating information on social determinants of health into our dataset, we have the opportunity to better understand the role of social support, education, housing, and other socioeconomic factors in contributing to cancer outcomes.”
“Through the REPRESENT study, Sema4 is delivering best-in-class standard of care to those in need while simultaneously creating one of the most diverse and racially comprehensive datasets for clinicians, researchers, payors, and pharma alike,” said Michelle Zimmerman, Chief Strategy & Transformation Officer, Sema4.
Sema4 will leverage its Sema4 Signal® precision oncology portfolio of next generation sequencing assays to uncover actionable insights from the dataset. Patient samples will be analyzed using Sema4 Signal Whole Exome Sequencing (WES)/Whole Transcriptome Sequencing (WTS) along with the company’s Hereditary Cancer, liquid biopsy, and pharmacogenomics testing. Sema4 researchers will use the resulting sequencing data, registry, and biobank to assess the prevalence of actionable biomarkers, driver mutations, germline alterations, and social determinants of health in these diverse populations. In addition, patients in the registry and biobank will be contacted if appropriate treatment options or clinical trials come available.
“Sema4’s REPRESENT study will facilitate access to precision oncology testing in underserved communities and increase the availability of diverse clinico-genomic data and biospecimens for the research community,” said Robert Winn, MD, Director of the VCU Massey Cancer Center and a Sema4 Oncology Advisory Board member. “The resulting dataset will enable Sema4 to leverage real-world data to uncover disparities and discover ways to better identify, treat, and monitor patients of all populations. The future of informed disparities work in the community begins today with initiatives like these.”
About Sema4
Sema4 is a patient-centered health intelligence company dedicated to advancing healthcare through data-driven insights. Sema4 is transforming healthcare by applying AI and machine learning to multidimensional, longitudinal clinical and genomic data to build dynamic models of human health and defining optimal, individualized health trajectories. Centrellis®, our innovative health intelligence platform, is enabling us to generate a more complete understanding of disease and wellness and to provide science-driven solutions to the most pressing medical needs. Sema4 believes that patients should be treated as partners, and that data should be shared for the benefit of all.
For more information, please visit sema4.com and connect with Sema4 on Twitter, LinkedIn, Facebook and YouTube.
Media contact:
Radley Moss
[email protected]
Artificial Intelligence
CleverTap launches Clever.AI, the AI-Driven Edge for Customer Engagement & Retention
Clever.AI will help brands achieve 66% higher conversion rates and 35% boost in operational efficiency
SAN FRANCISCO and MUMBAI, India, May 3, 2024 /PRNewswire/ — CleverTap, one of the leading all-in-one customer engagement and retention platforms, today announced the launch of Clever.AI, its AI engine. With Clever.AI, CleverTap seeks to enable brands with the next generation of AI capabilities required to build human-like understanding of customers and deliver personalized experiences efficiently that resonate with them, ultimately maximizing customer lifetime value.
Clever.AI is built on the foundation of three core AI pillars – Predictive, Generative, and Prescriptive. Clever.AI propels these three pillars to transform the way brands engage with customers and make customer interactions more intelligent, and efficient.
Clever.AI enables brands to become:
Insightful: With Predictive AI capabilities, it forecasts precise business outcomes, helping brands to anticipate customer needs. Clever.AI’s insights are powered by CleverTap’s proprietary TesseractDB™ which ensures data granularity with an extended lookback period, making predictions more accurate, and enabling brands to make informed decisions, resulting in improved marketing ROIEmpathetic: Taking GenAI forward, Clever.AI merges creativity with emotional intelligence, crafting content that resonates on a human level. This empathetic approach helps brands drive higher conversions and engages customers with hyper-personalized experiencesActionable: Leveraging Prescriptive AI capabilities, it provides actionable recommendations to maximize conversions throughout the customer journey by helping brands identify the optimal engagement strategies in real-timePeter Takacs, Digital Product Manager, Burger King said, “I would rate it 10 for its ease of use and numerous possible use cases. We uplifted our marketing campaigns by easily experimenting with multiple possibilities and quickly converging on the optimum one. It opens up a new era of continuous experimentation for us.”
Anand Jain, Co-founder and Chief Product Officer, CleverTap said, “We’re thrilled to unveil Clever.AI, a testament of our pursuit over the last several years in leading the way in adopting the latest tech to transform customer engagement. We will continue to innovate CleverTap’s All-in-One engagement platform with Clever.AI enhancing its precision in predictions, its ability to prescribe intelligent customer experiences strengthened by advanced product analytics and deeper persona profiling to ensure brands can build highly personalized experiences, and campaigns more effectively, ensuring every customer interaction is personalized and outcome driven.”
With Clever.AI, brands have already experienced a boost in conversion with significantly higher operational efficiency. They witnessed a 66 percent increase in conversion rates, 35% boost in operational efficiency and a 3x improvement in click-through rates (CTRs), with an increase across metrics such as purchases, and average order values (AOVs). Moreover, Clever.AI enhanced operational efficiency by simplifying campaign roll-outs, content creation, and experimentation at scale. Clever.AI has helped leading brands like TouchnGo, Swiggy, Burger King add efficiency to their campaigns.
CleverTap will unveil its new AI capabilities through its Spring Release ’24 event slated from 6th May to 9th May, through a series of thought-provoking sessions on how AI can make campaigns more intelligent, efficient, and engaging for brands.
About CleverTap
CleverTap is the all-in-one engagement platform that helps brands unlock limitless customer lifetime value by helping them create personalized experiences to retain their most valuable customers. The platform empowers businesses to orchestrate experiences for individuals across their lifecycles and design personalized journeys that span a lifetime. It offers analytics that encompasses every aspect of the lifecycle, enabling businesses to measure and optimize each experience in real-time. Its unique AI capability is insightful, empathetic, and prescriptive, facilitating smarter and faster decisions. The all-in-one platform unifies experiences from every touchpoint, paving the way for a new era of customer engagement.
The platform is powered by TesseractDB™ – the world’s first purpose-built database for customer engagement, offering both speed and economies of scale.
CleverTap is trusted by 2000 customers, including Electronic Arts, TiltingPoint, Gamebasics, Big Fish, MobilityWare, TED, English Premier League, TD Bank, Carousell, AirAsia, Papa John’s, and Tesco.
Backed by leading investors such as Peak XV Partners, Tiger Global, Accel, CDPQ, and 360 One, the company is headquartered in San Francisco, California, with presence in New York, São Paulo, Bogota, London, Amsterdam, Sofia, Dubai, Mumbai, Bangalore, Delhi, Singapore, Jakarta, and Ho Chi Minh.
For more information, visit clevertap.com or follow us on: LinkedIn: https://www.linkedin.com/company/clevertap/X: https://twitter.com/CleverTap
Forward-Looking Statements
Some of the statements in this press release may represent CleverTap’s belief in connection with future events and may be forward-looking statements, or statements of future expectations based on currently available information. CleverTap cautions that such statements are naturally subject to risks and uncertainties that could result in the actual outcome being absolutely different from the results anticipated by the statements mentioned in the press release.
Factors such as the development of general economic conditions affecting our business, future market conditions, our ability to maintain cost advantages, uncertainty with respect to earnings, corporate actions, client concentration, reduced demand, liability or damages in our service contracts, unusual catastrophic loss events, war, political instability, changes in government policies or laws, legal restrictions impacting our business, impact of pandemic, epidemic, any natural calamity and other factors that are naturally beyond our control, changes in the capital markets and other circumstances may cause the actual events or results to be materially different, from those anticipated by such statements. CleverTap does not make any representation or warranty, express or implied, as to the accuracy, completeness, or updated or revised status of such statements. Therefore, in no case whatsoever will CleverTap and its affiliate companies be liable to anyone for any decision made or action taken in conjunction.
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Artificial Intelligence
Appian Named a Leader in the 2024 Gartner® Magic Quadrant™ for Process Mining Platforms Report
LONDON, May 3, 2024 /PRNewswire/ — Appian (Nasdaq: APPN) today announced it has been named a Leader by Gartner in its 2024 Magic Quadrant for Process Mining Platforms report. The report evaluated 18 vendors and their product offerings. For more information, download a complimentary copy of the Gartner Process Mining 2024 report.
Gartner defines Process Mining platforms as tools that deliver visibility and insights to technology innovation leaders that enable smart decision making and strong performance on an organisation’s critical priorities. Features that make Appian a leader in Process Mining, include:
Faster data prep that eliminates complex transformation with always-ready data from multiple sources.Automated process analysis and intelligent recommendations for where and how to take action.A low-code experience for measuring, monitoring, and optimising process performance—all within one platform.”We believe that Appian’s recognition in the Gartner Process Mining Platforms Magic Quadrant underscores our dedication to process excellence. Through Process HQ, we integrate data fabric, process mining, machine learning, and generative AI to streamline manual data prep, enabling businesses to gain insights swiftly and implement improvements easily,” said Michael Beckley, CTO and Founder of Appian. “Our unified approach merges Process Mining with AI-driven process automation, setting a new standard for efficiency and intelligence.”
Business users need greater visibility into the full breadth of their enterprise data and processes in order to maximise operational efficiency and strategic decision-making. By combining the latest technologies in data fabric, process mining, machine learning, and generative AI, Process HQ helps monitor and improve every business process built on Appian. Process HQ makes it easy to reduce costs, risks, and delays, improve compliance, and drive better business outcomes, without the need for costly and time-consuming data collection efforts.
Appian is now an industry leader across its value proposition to Design, Automate, and Optimise the most complex business processes. In addition to today’s announcement, Appian was named a Leader in the 2023 Gartner® Magic Quadrant™ for Enterprise Low-Code Application Platforms report, and was ranked #1 for the Business Workflow Automation with Integration Use Case in the 2023 Gartner® Critical Capabilities for Enterprise Low-Code Application Platforms (LCAP) report.
To access the report and to learn more about Appian’s positioning, visit https://ap.pn/3y2ClZy. Register for our upcoming webinar Process Intelligence Made Easy: The Key to Better Business Decisions on June 20, 2024 at 12pm EST to discover how Process HQ can improve business processes.
Gartner disclaimerGartner does not endorse any vendor, product or service depicted in our research publications, and does not advise technology users to select only those vendors with the highest ratings or other designation. Gartner research publications consist of the opinions of Gartner research organisation and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose. GARTNER is a registered trademark and service mark of Gartner and Magic Quadrant is a registered trademark of Gartner, Inc. and/or its affiliates in the U.S. and internationally and are used herein with permission. All rights reserved.
About Appian
Appian is a software company that automates business processes. The Appian AI Process Platform includes everything you need to design, automate, and optimise even the most complex processes, from start to finish. The world’s most innovative organisations trust Appian to improve their workflows, unify data, and optimise operations—resulting in better growth and superior customer experiences. For more information, visit appian.com. [Nasdaq: APPN]
Follow Appian: LinkedIn, X, and X (UK).
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Artificial Intelligence
Innodisk Introduces iCAP Air: Advancing Air Quality Management through Autonomous Decision-Making
TAIPEI, May 3, 2024 /PRNewswire/ — Innodisk, a global leader in AI solutions, has taken a pivotal step forward in environmental sustainability with the launch of its latest innovation, the “iCAP Air” air quality management solution. This solution empowers businesses worldwide to enhance air quality, sustainability, and human health. Additionally, business can benefit from monthly AI-generated air quality data report, providing valuable insights for informed decision-making.
Leveraging its expertise in edge computing and software and hardware integration, along with the expertise of its subsidiary Sysinno in air quality detection, Innodisk has achieved the development of the “iCAP Air” air quality management solution. This solution integrates advanced technology, including the innovative “iAeris7” air quality detector from Sysinno, to deliver accuracy in detecting temperature, humidity, fine suspended particles (PM2.5), suspended particles (PM10), carbon dioxide (CO2), formaldehyde and total volatile organic compounds (TVOC). It can also be customized to detect NO2, SO2, CO, NH3, and other air factors. At the same time, the iAeris7 device is known for its reliability, patented technology, and various international certifications, including those from SGS and FCC/CE/RoHS/NCC/BSMI.
The solution also includes the “iCAP Air Server,” designed to manage large-scale deployment and data from up to 100 air quality detectors, ensuring seamless integration and efficient operation, even in complex environments. Additionally, iCAP Air provides a user-friendly air quality management platform, enabling organizations to monitor air quality in real-time via a mobile app or internet browser, receive automatic alerts, and optimize air purification or exhaust ventilation system.
iCAP Air is a comprehensive solution that simplifies air quality management for users. It is tailored for medium to large-sized sites or densely populated, enclosed spaces such as medical institutions, smart manufacturing facilities, public transportation hubs, indoor parking facilities, and department stores. Innodisk’s “iCAP Air” air quality management solution represents a milestone for all businesses committed to leveraging technology for the greater good of air quality and society.
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