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Alzheimer’s Disease Emerging Tools Report 2023: Unmet Need for Early and Non-Invasive Diagnostic Techniques Fuels Growth

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Dublin, May 09, 2023 (GLOBE NEWSWIRE) — The “Emerging Tools for Alzheimer’s Disease” report has been added to ResearchAndMarkets.com’s offering.

The report provides an overview of AD, and the current diagnostic methods. The report explains the need for emerging tools for the early detection of the disease. Tools that have been approved are discussed, as well as tools in the development phase. The report does not include therapeutics approved or in the pipeline for AD.

The report covers the global market for emerging tools with a look at the regional markets of North America, Europe and Emerging Markets.

Alzheimer’s disease (AD) is a neurodegenerative disease that progresses along a continuum from preclinical disease to mild cognitive and behavioral impairment and finally dementia. Existing diagnosis methods include cognitive assessments, positron emission tomography (PET) scans, magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) tests. All these diagnostic methods are not routinely used for diagnosis as they are expensive and invasive. As a result, there is a substantial unmet need for earlier diagnosis with more cost-effective and less invasive procedures.

There is high demand for tests that are cost-, resource- and time-effective and that would help in the screening of suitable patients for clinical trials and also lead to early detection of the disease.

Notably, the development of effective drugs that can prevent, treat and cure AD begins with the ability to accurately diagnose people at an early stage of the disease. The recent approval of drugs by the U.S. Food and Drug Administration (FDA) for the treatment of early Alzheimer’s disease is a significant driver of demand for early detection.

In 2021, the FDA granted accelerated approval to aducanumab, and in 2023 it granted accelerated approval to lecanemab. Aducanumab works by removing beta-amyloid from the brain, while Lecanemab works by blocking the formation of amyloid plaques in the brain. Other anti-amyloid monoclonal antibodies (mAbs) are in late-stage development and target the early stage of the disease.

Extensive research is ongoing for blood-based biomarker tests that are easily performed and inexpensive. Studies have indicated that these tests help improve the design of clinical trials for disease-modifying agents. The role of blood-based biomarkers includes primary care screening, diagnostics, predictive risk, i.e., risk for incident AD, risk for progression from mild cognitive impairment (MCI) to AD, disease monitoring, stratification into clinical trials, and pharmacodynamic or treatment response monitoring (positive or adverse). Research is also ongoing for digital biomarkers and tools that are based on artificial intelligence (AI) and other advanced technologies.

Blood tests authorized for clinical and research use include PrecivityAD from C2N Diagnostic; Quest AD-Detect from Quest Diagnostics; the HISCL ß-Amyloid 1-42 and 1-40 Assay Kits from Sysmex; and AlzoSure Predict from Diadem have launched their blood-based biomarkers products for clinical use. Products from other companies such as Fujirebio and Roche are for research use only. Retinal products from Optina Diagnostics and Cognoptix have also been authorized for research use only.

The global market for emerging AD tools was valued at $814.7 million in 2022 and is forecast to grow at a CAGR of 13.6% to reach a value of $1.7 billion by the end of 2028. This growth rate is attributed to the increasing prevalence of the disease, high demand in the market, many product approvals and launches in the forecast period, and extensive R&D efforts, increasing investments and funding, and the need to recruit the right patients for clinical trials. The North American region accounts for the highest share of the global market due to expenditures for extensive R&D, the presence of many major players, and increasing authorizations by the FDA.

Report Includes

  • An overview of the global market for emerging tools for the early detection of Alzheimer’s disease
  • Estimation of the market size and analyses of global market trends, with data from 2020 to 2022, estimates for 2023 with projections of compound annual growth rates (CAGRs) through 2028
  • Highlights of the current and future market potential and quantification of market based on type and region
  • Identification of market drivers, restraints and other forces impacting the global market and evaluation of current market size and forecast
  • Detailed analysis of the regulatory framework and policies and product pipeline of the industry
  • Market share analysis of the key companies of the industry and coverage of their proprietary technologies, strategic alliances, and other key market strategies and a relevant patent analysis

Key Topics Covered:

Chapter 1 Market Outlook
1.1 Market Snapshot

Chapter 2 Executive Summary

Chapter 3 Market Overview and Technology Background
3.1 Overview
3.2 Pathogenesis
3.3 Causes and Risk Factors
3.4 Diagnosis
3.5 Treatment

Chapter 4 Emerging Tools and Technologies

Chapter 5 Market Dynamics
5.1 Factors Affecting the Market for Emerging Tools for Ad
5.2 Market Drivers
5.2.1 Increasing Prevalence of Alzheimer’s Disease
5.2.2 High Unmet Need
5.2.3 Need to Identify the Right Patients for Clinical Trials
5.2.4 Increasing Investments and Funding
5.3 Market Restraints
5.3.1 Technological Challenges
5.3.2 Ethical Challenges
5.3.3 Reimbursement Challenges
5.4 Opportunities
5.5 Impact of Covid-19

Chapter 6 Emerging Tools for Alzheimer’s Disease
6.1 North America
6.2 Europe
6.3 Emerging Markets

Chapter 7 Competitive Landscape and Analysis of Market Opportunities
7.1 Strategic Initiatives
7.2 Competitive Analysis

Chapter 8 Company Profiles

Chapter 9 Project Scope and Methodology

Companies Mentioned

  • Altpep
  • Araclon Biotech
  • C2N Diagnostics LLC
  • Cognoptix
  • Diadem Spa
  • F. Hoffmann-La Roche AG (Roche)
  • Fujirebio Diagnostics
  • Quanterix Corp.
  • Quest Diagnostics Inc.
  • Sysmex Corp.

For more information about this report visit https://www.researchandmarkets.com/r/j18to0

About ResearchAndMarkets.com
ResearchAndMarkets.com is the world’s leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.


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Artificial Intelligence

Dongfa Group’s Gas Scenario + Digital Twin Technology, Leads the Industry with New AI Trend

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–Highlights of the 2024 Exhibition
SHANGHAI, May 23, 2024 /PRNewswire/ — From May 17 to 19, 2024, China(Shanghai) International Metrology Measurement Technology and Equipment Exhibition was held at the Shanghai World Expo Exhibition and Convention Center. Dongfa Group participated in the exhibition, showcasing its latest research achievements. At the expo, Chairman Liu Ming of Dongfa Group conducted the lighting ceremony and announced the official launch of the “Smart Gas Comprehensive Supervision Platform,” demonstrating the convenience and efficiency achieved through the smart management of municipal gas meters.

Dandong Dongfa (Group) Co., Ltd., established in 1962 and headquartered in Singapore, was formerly known as Dandong Thermal Instrument Co., Ltd. As an integrated group company engaged in research, production, and operations, Dongfa Group is dedicated to the development and application of instruments and meters. Its product range includes IC card gas meters, wired direct-reading remote diaphragm gas meters, wireless direct-reading remote diaphragm gas meters, NB-IoT IoT meters, and ultrasonic gas meters. These products incorporate the technical features of similar domestic and international products, offering high accuracy, reliability, and stability, making the company a leading smart gas meter manufacturer in China.
At the expo, Dongfa Group showcased its Smart Gas Comprehensive Supervision Platform, which integrates AI, IoT, cloud computing, and big data. This platform connects the topological structure of all aspects of gas operations and consolidates all relevant data involved in production management and operation maintenance. This integration enhances the comprehensive research and development and operational maintenance capabilities of the big data governance system.
At the same time, Dongfa Group is empowering comprehensive management and control with digital twins, AI, and big data. By leveraging digital twins, AI models, and 5G technology as data elements, the company is constructing a unified citywide network and a digital twin map of the gas pipeline network. This enables deep integration of AI monitoring, pressure and leakage detection, smart terminals, and other sensing devices with gas operations, ensuring the comprehensive safety and supply of urban gas.
Digital twin gas technology not only provides auxiliary support for pipeline design, but also plays a crucial role in intelligent emergency response and precise distribution. Especially in the operation of gas stations, it enables comprehensive real-time monitoring, intelligent integrated operation scheduling, proactive warning, emergency event command plans, and other effects, thereby improving the efficiency and safety of gas management.
However, there have been numerous incidents of data leakage involving smart AI devices in recent years. Sensitive data is being collected or even sold by malicious actors, leading to the disclosure of confidential information, resulting in significant economic losses and even legal risks.
To ensure the security of both enterprise and user data, Dongfa Group utilizes Digital Envelope technology to encrypt and decrypt data packets during data collection and distribution. This approach combines the advantages of both symmetric and asymmetric encryption technologies for secure information transmission, enabling fast, efficient, and secure encryption and decryption processing for the smart gas digital business sector. This ensures the security and integrity of data during transmission.
Visitors at the expo showed strong interest in the new products and technologies exhibited by Dongfa Group. Dongfa Group has always been committed to driving the development of the smart instrumentation industry through technological innovation. Through this exhibition, the company not only showcased its technical prowess but also strengthened communication and collaboration with industry peers. Looking ahead, they aim to join hands in opening a new chapter in the smart instrumentation industry.
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QNAP S3-compatible Storage Solution “QuObjects” Certified as Veeam® Ready – Object with Immutability

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TAIPEI, May 23, 2024 /PRNewswire/ — QNAP® Systems, Inc., a leading computing, networking, and storage solution innovator, today announced that its S3-compatible object storage solution “QuObjects” has qualified as Veeam® Ready – Object with Immutability, applicable for QNAP NAS with QTS and QuTS hero operating systems. This certification underscores the reliability of QuObjects as a secure object backup solution for enterprises, enhancing data management efficiency and upmost security.

QuObjects is the S3 object storage solution for QNAP NAS, boasting read/write speeds 20 times faster than conventional cloud services, along with a highly flexible and scalable architecture to ensure efficient transmission and flexibility in object storage. From object service development to demanding workloads like machine learning and data lakes, QuObjects assists enterprises in achieving diverse application needs with higher cost effectiveness.
QuObjects supports Object Lock to ensure data immutability, further safeguarding against ransomware threats, cyberattacks, or human error. Coupled with access controls and authentication features, it provides comprehensive protection for object data security.
Jimmy Tam, Product Manager of QNAP, stated “Data security is critical for enterprises. With QuObjects certified by Veeam Ready – Object with Immutability, we empower organizations leveraging Veeam solutions to confidently opt for QNAP NAS for on-prem S3 object storage and backup, enjoying rapid transmission, extensive scalability, and steadfast security.”
QNAP is the preferred partner for Veeam object backup solutions. Learn more at Veeam Ready Object Partner and QNAP QuObjects- S3 Object Storage.
For more information and to view the full QNAP NAS lineup, please visit www.qnap.com.
Photo – https://mma.prnewswire.com/media/2413244/PR_image_QNAP_x_Veeam_Ready_en.jpg

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Tencent Announces Winners of Flagship CarbonX Program to Combat Climate Change

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SHENZHEN, China, May 23, 2024 /PRNewswire/ — Tencent (00700.HK) is awarding 13 exceptional teams that won the first phase of its groundbreaking CarbonX Program, which is aimed at boosting promising new climate technologies. The winners, which emerged from a pool of 30 finalists and more than 300 initial applications, will receive a total of around RMB 100 million (US$14 million) in financial support from Tencent. It showcases the company’s commitment to driving sustainable social innovations in the fight against climate change.

CarbonX was launched in March 2023 to advance the next generation of low-carbon technologies. Tencent has committed RMB 200 million (US$28 million) in catalytic funding over the next three years to innovative ideas that might otherwise languish or fail to gain traction.
CarbonX’s first phase focused on carbon capture, utilization, and storage (CCUS), as well as technology-based carbon removal. These solutions were chosen for their unique ability to curb emissions from hard-to-abate industries such as steel and cement, mitigate the continued reliance on fossil fuels, and reduce legacy emissions created from decades of industrialization.
Backed by Tencent’s mission of Tech for Good and an alliance of like-minded industry partners, CarbonX aims to help these cutting-edge technologies make the leap from the research or early startup stage to commercial scale. The ultimate goal is supporting them in making a significant impact toward the targets outlined in the Paris Agreement, which includes a 45 percent reduction in emissions by 2030 and achieving net-zero emissions by 2050.
Dr. Hao Xu, Tencent’s Vice President of Sustainable Social Value and Head of Tencent’s Carbon Neutrality Lab, said: “Technology innovation serves as the driving force to accelerate our progress toward achieving carbon neutrality. CarbonX program is aimed at fostering the growth of these technologies, driving positive impact across society, and laying the groundwork for a more sustainable future.”
Professor Jerry Yan, Chair Professor of the Hong Kong Polytechnic University and Co-chairman of the CarbonX expert committee, said: “To pave the path for a greener economy, we must champion the development of cutting-edge low-carbon technologies. Just as solar and wind power were nurtured in their infancy, emerging solutions like CCUS and tech-based carbon removal demand our early support.”
The program assembled a panel of experts from academia, industries, and the investor community as the jury, and welcomed submissions from diverse participants across three distinct tracks:
CarbonX Lab: Designed to incubate research institutions, universities, or labs that bring in game-changing climate solutionsCarbonX Accelerator: Designed to accelerate the growth of climate-tech startups that exhibit commercialization potentialCarbonX Infrastructure: Designed to support capacity building to facilitate industry developmentThe finalists comprise four projects from the Lab track, six from the Accelerator track, and three from the Infrastructure track. These projects explore innovative solutions, such as using steel slag to capture and store carbon directly from furnace exhaust, converting CO2 into sustainable aviation fuel and valuable chemicals through electrochemical reactions or microorganisms, and employing new approaches to directly capture CO2 from the atmosphere with the hope of slashing the cost to less than US$150 per ton.
Meanwhile, Tencent is also collaborating with Tsinghua University to develop a comprehensive system of Measure, Reporting and Verification (MRV) tools to accurately gauge progress toward decarbonization.
Aside from receiving financial and advisory support, several projects will also have the opportunity to collaborate with industry partners and test their research beyond the laboratory setting.
Building upon the success of the first phase, Tencent is poised to launch the second iteration of CarbonX globally as early as later this year in pursuit of early-stage climate tech innovation.

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