Artificial Intelligence
ProPhase Labs Teams up with Certis Oncology to Accelerate Development of Novel Linebacker Compound
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Garden City, NY, Aug. 03, 2023 (GLOBE NEWSWIRE) — ProPhase Labs, Inc. (NASDAQ: PRPH) (“ProPhase”), a next generation biotech, genomics, therapeutics and diagnostics company, today provided an update regarding its progress and development strategy for Linebacker-1 (LB-1), a small molecule, multi-kinase inhibitor that is being developed by the Company’s wholly owned subsidiary, ProPhase BioPharma, Inc. (“PBIO”), as a potential safer, more efficacious oncology therapy wholly unlike standard chemotherapeutic agents.
“ProPhase Labs continues to act as a disruptor in the therapeutic development space by employing only the most advanced, cutting-edge technology in the pursuit of clinical benefit and program success,” commented developmental lead Dr. Matt Halpert Ph.D. “Long gone are the days of blind experimentation with the hopes of achieving promising results.. We have entered an era in which if you are not at the forefront of high throughput analysis and technology for therapeutical development, you are not in therapeutical development.” With that mindset, ProPhase Labs has joined forces with Certis Oncology to use one-of-a-kind, robust, machine learning technology to exponentially improve the chances of successful development in the oncological therapeutic space.
“We have tested the novel Linebacker compound against hundreds of cancers and thousands of pathways, but will continue testing to the extent we believe useful data may be obtainable,” says Ted Karkus, CEO of ProPhase Labs. “By further mining all existing data sets, we are able to cross-reference genetic signatures, signaling pathways, and Linebacker responsiveness with Artificial Intelligence (AI), which we believe will greatly assist us in honing in on the most likely cancers and pathways that may be inhibited by Linebacker in the big picture.”
“Using Certis’s proprietary technology, CertisAI Predictive Oncology Intelligence™, we determined that Linebacker may be effective against several types of cancer, but importantly not all cancers,” Dr. Halpert continued. “Selectivity is good, and being able to determine now what is most likely to be clinically relevant only improves the overall odds of success.” ProPhase intends to continue to line up AI-generated information with sound medical and scientific insights from experienced players to further guide development towards a regulatory pathway with lower barriers to entry and severe need in the clinic.
“Our team is very pleased to be working with ProPhase on the Linebacker initiative. By leveraging the predictive power of artificial intelligence and machine learning, then validating in silico predictions using advanced, more clinically relevant biological models of cancer, the scientific community will answer complex questions about how to treat each unique cancer—faster,” said Peter Ellman, President and CEO of Certis.
“Of course, this is more work on the front end, but it would be short-sighted and disingenuous to forego these opportunities to protect against a future, exponentially larger, burn,” added Karkus. “Savvy investors expect this now, and with good reason, and ProPhase will continue to lead the pack and push the boundaries forward. We are looking forward to initiating Phase I human studies next year at a modest budget of approximately $3+ million dollars for all planned studies. This is a nominal amount given our greater than $40 million in net working capital. With positive results and subject to the necessary regulatory approvals, we believe we will be well situated to explore significant licensing opportunities with major pharma.”
With this extensive data set now in hand, ProPhase will proceed to the next level of IND-enabling development for the potentially revolutionary Linebacker drug. Focused and detailed studies are already underway.
About Linebacker
Linebacker is a modified polyphenol. Polyphenols are substances found in many nuts, vegetables and berries. Linebacker compounds are modified Myricetin, which is a common plant-derived flavonoid. Myricetin exhibits a wide range of activities that include strong antioxidant, anti-cancer, antidiabetic and anti-inflammatory activities. It displays activities that are related to the central nervous system.
LB-1 is Mono-chlorinated Myricetin with a Chlorine atom substituted for the Hydroxy group at 5’ (position 5 on the B-ring). LB-2 is Di-chlorinated Myricetin with Chlorine atoms substituted for the Hydroxy groups at 5’ and 7 (position 5 on the B-ring and position 7 on the A-ring).
About Certis Oncology Solutions, Inc.
Certis is a precision oncology and translational science company. Its product is “Oncology Intelligence™”—highly predictive therapeutic response data derived from advanced models of cancer. We partner with oncology therapeutics developers to help close the problematic translation gap between preclinical studies and clinical trials. Using our proprietary artificial intelligence/machine learning platform and more clinically relevant, patient-derived tumor models, we bring certainty to lead candidate selection and help secure clear and compelling evidence of drug efficacy. Established in 2016, Certis operates a CLIA-certified laboratory in Sorrento Valley, the heart of San Diego’s life sciences industry.
About ProPhase Labs
ProPhase Labs, Inc. (Nasdaq: PRPH) (“ProPhase”) is a next-generation biotech, genomics, therapeutics and diagnostics company. Our goal is to create a healthier world with bold action and the power of insight. We’re revolutionizing healthcare with industry-leading Whole Genome Sequencing solutions, while developing potential game changer diagnostics and therapeutics in the fight against cancer. This includes a potentially life-saving cancer test focused on early detection of esophageal cancer and potential breakthrough cancer therapeutics with novel mechanisms of action. Our world-class CLIA labs and cutting-edge diagnostic technology provide wellness solutions for healthcare providers and consumers. We develop, manufacture, and commercialize health and wellness solutions to enable people to live their best lives. We are committed to executional excellence, smart diversification, and a synergistic, omni-channel approach. ProPhase Labs’ valuable subsidiaries, their synergies, and significant growth underscore our multi-billion-dollar potential.
Forward Looking Statements
Except for the historical information contained herein, this document contains forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding our strategy, plans, objectives and initiatives, our beliefs regarding the potential of Linebacker-1 to be a safer, more efficacious oncology therapy, the potential for artificial intelligence to improve the Company’s chances of successful development of Linebacker-1, and the projected timelines for the Company’s preclinical and clinical programs and commercialization. Management believes that these forward-looking statements are reasonable as and when made. However, such forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause actual results to differ materially from those projected in the forward-looking statements. These risks and uncertainties include but are not limited to our ability to obtain and maintain necessary regulatory approvals, general economic conditions, consumer demand for our products and services, challenges relating to entering and growing new business lines, the competitive environment, and the risk factors listed from time to time in our Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q and any other SEC filings. The Company undertakes no obligation to update forward-looking statements except as required by applicable securities laws. Readers are cautioned that forward-looking statements are not guarantees of future performance and are cautioned not to place undue reliance on any forward-looking statements.
For more information, visit www.ProPhaseLabs.com
Media Relations and Institutional Investor Contact:
ProPhase Labs, Inc.
267-880-1111
[email protected]
Retail Investor Relations Contact:
Renmark Financial Communications
John Boidman
514-939-3989
[email protected]
Source: ProPhase Labs, Inc.
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Artificial Intelligence
TECNO Pocket Go Wins Global Product Technology Innovation Award 2024 at IFA 2024
![tecno-pocket-go-wins-global-product-technology-innovation-award-2024-at-ifa-2024](https://roboticulized.com/wp-content/uploads/2024/09/153023-tecno-pocket-go-wins-global-product-technology-innovation-award-2024-at-ifa-2024.jpg)
BERLIN, Sept. 7, 2024 /PRNewswire/ — One of the largest consumer electronics exhibitions in the world, the 2024 IFA Berlin International Consumer Electronics Show, officially kicks off today in Berlin. During the event, the highly anticipated Global Product Technical Innovation Award 2024 was announced, with TECNO Pocket Go winning the prestigious AR Immersive PC Gaming Experience Innovation Gold Award. This recognition highlights the brilliance of Chinese brand on the global stage.
TECNO is dedicated to innovation from the user’s perspective, continuously developing products and applications that enhance user experience. Since 2019, TECNO has expanded its AIoT ecosystem, leveraging its mobile technology to introduce innovative smart wearables, business laptops, and other groundbreaking products, all aimed at providing users with a more intelligent TECNO ecosystem experience.
As a global innovative technology brand with operations in over 70 markets, TECNO has been committed to revolutionizing the digital experience in global emerging markets, relentlessly pushing for the perfect integration of contemporary, aesthetic design with the latest technologies. TECNO offers a wide range of AIoT products covering smart wearables, laptops, tablets and smart home products.
Guided by its brand essence of “Stop At Nothing”, TECNO is committed to unlocking the best and newest technologies for forward-looking individuals, inspiring them to never stop pursuing their best selves and their best futures.
The “Global Product Technology Innovation Award” is a grand international selection of global consumer electronics brands. Launched globally every year, it is also one of the most professional and authoritative international exchange, display and cooperation platforms in IFA in the same year to conduct comprehensive review and evaluation of the global consumer electronics industry for the whole year.
TECNO Pocket Go, redefines gaming on the go
TECNO Pocket Go creates a “new gaming paradise” in handheld PC form in AR industry. By seamlessly integrating with the Windows gaming ecosystem and utilizing advanced head tracking technology, it brings an unparalleled 6D immersive experience to users. Featuring a top-tier AMD® Ryzen™ 7 8840HS gaming processor and a laptop level cooling system by rebuilt the structure to compact size with 50% smaller size and 30% lighter weight. Just easy to carry as a smartphone.
Smaller in your palm, Master in your vision
The AR Pocket Vision features a 0.71-inch Micro-OLED screen that delivers the equivalent of a 215-inch TV experience from 6 meters away, surpassing industry standards. Gamers will enjoy a cinematic-level viewing experience, with customizable adjustments for up to 600° diopters to ensure eye comfort. It also safeguards your privacy, enabling you to play anywhere.
Dominant Flagship Gaming CPU, lead Performance Ahead
Powered by the AMD® Ryzen™ 7 8840HS gaming processor, the Pocket Go handheld offers exceptional speed and seamless multitasking with 8 cores, 16 threads, and turbo speeds up to 5.1 GHz. Its PC-level cooling system, featuring a large fan and three copper pipes, ensures optimal performance at 35W. Combined with a 50Wh replaceable battery, it guarantees long-lasting gaming sessions without interruptions.
“VisionTrack” experiences, games come alive
The Pocket Go combo delivers an immersive experience for your eyes and hands. The AR Pocket Vision features a six-axis gyroscope and AI algorithms for precise head tracking, enhancing real-time data collection during gameplay. With N’BASS® acoustic materials and a proprietary vibration algorithm, it translates in-game sounds into nuanced vibrations via handheld while the Hall Effect Joysticks and Triggers provide precise control, elevating your gaming experience with rich visual and tactile sensations.
With TECNO Pocket Go, users can enjoy a futuristic gaming experience, and seamlessly connecting to TECNO’s products in a new forms of AR experiences.
View original content:https://www.prnewswire.co.uk/news-releases/tecno-pocket-go-wins-global-product-technology-innovation-award-2024-at-ifa-2024-302241146.html
Artificial Intelligence
Experience the Future of Smart Living with Hisense at IFA 2024
![experience-the-future-of-smart-living-with-hisense-at-ifa-2024](https://roboticulized.com/wp-content/uploads/2024/09/153019-experience-the-future-of-smart-living-with-hisense-at-ifa-2024.jpg)
QINGDAO, China, Sept. 7, 2024 /PRNewswire/ — Hisense, a global leader in home appliances and consumer electronics, unveiled its innovative smart home solutions at IFA 2024. Based on the theme “The Scenario-driven Future of Tech,” Hisense showcased its latest smart home appliances and the ConnectLife app, designed to seamlessly connect appliances and real-life scenarios to redefine how users interact with their homes.
Focused on enhancing the user experience, Hisense’s booth at IFA 2024 brings to life three smart scenarios and products that aim to make the future of smart living more intuitive and accessible: Smart Laundry, Smart Kitchen and Smart Air Care.
Each experience is developed through Hisense’s scenario-driven research and development approach that prioritizes real user needs:
Smart Laundry simplifies garment care with automated adjusting and remote monitoring.Smart Kitchen streamlines cooking with connected appliances that personalize meal prep.Smart Air Care ensures a healthier living environment by intelligently adjusting air quality.To bring the smart living scenarios to life, Hisense has introduced a range of innovative products that integrate seamlessly with the ConnectLife app.
The Hisense Refrigerator PureFlat Smart Series exemplifies the premium smart kitchen experience enabled by ConnectLife. Equipped with a 21-inch TFT touchscreen, this refrigerator offers a wealth of features. The AI Recipe feature leverages food inventory tracking to suggest personalized recipes based on available ingredients and their expiration dates. Serving as a home appliance control center, the ConnectLife Hub refrigerator allows you to adjust temperature settings remotely through the ConnectLife app. Additionally, its AI Eco feature enables you to activate energy-saving mode on your device with a simple touch. With dual-tech cooling system, a My Fresh Choice compartment, and an on-door ice and water dispenser, this refrigerator delivers efficient temperature control, flexible storage options, and convenient access to cold beverages.
The Hisense Series 7i washing machines offer a superior laundry experience with a suite of smart features. The iPlay™ Intelligent Display provides a user-friendly interface, while the iJet™ three-channel spray system ensures a thorough wash. The compact iFit™ feature allows for easy integration into cabinets, optimizing space. AI-powered capabilities enhance performance with AI Super Wash, which intelligently adjusts washing parameters based on load weight, material type, water level, hardness, and turbidity. The AI Super Dry program in the Series 7i tumble dryer delivers precise drying with 3D Humidity Sensor for accurate moisture detection.
The Hisense’s Hi8 Series Oven offers a range of cooking functions, including air-frying, fast preheating, and pizza mode. Its large capacity and cool-touch doors make it easy to cook with and also clean. The VisonPlus Screen provides a user-friendly interface for exploring cooking programs and settings. Cleaning is made simple with features including Steam Clean Pro, Pyrolytic Self Clean, and Removable Door&Glass. The Hisense Hi 9 Series Oven is a premium model that offers advanced features such as AI-powered InCamera Technology for intelligent baking, Auto Door Opening & Auto Lock. Its larger TFT screen provides a user-friendly interface for exploring over 140 pre-programmed recipes and cooking settings. With ConnectLife integration, the Hi 9 delivers a convenient and efficient cooking experience.
Hisense Energy Pro X air conditioners offer efficient cooling and heating with advanced, energy-saving features. The AI Smart Airflow adjusts airflow direction based on your position and needs, ensuring optimal comfort. HI-NANO technology enhances air quality by releasing high-concentration ions to eliminate 92.6% of H1N1, 88.54% of E. coli, and 60.07% of PM2.5 in two hours. The TMS Control System intelligently adjusts temperature and humidity by analyzing various indoor conditions, providing a tailored and comfortable environment.
Beyond residential air conditioning, Hisense Hi-Therma ATW heat pump is another popular option for room heating, especially in Europe. Renowned for their outstanding performance and eco-friendly features, Hisense Hi-Therma II R290 ATW boasts an A+++ energy efficiency rating, stable operation at temperatures as low as -25°C, and maximum water outlet temperature of 65°C, with the flexibility to control up to 7 independent rooms. Moreover, the first-generation Hi-Therma Split (R32) finished the rigorous winter test conducted by Germany’s VDE and obtained the No. 001 certification in the extremely cold city of Mohe, China.
About Hisense
Hisense is a leading global home appliance and consumer electronics brand and official partner of the UEFA EURO 2024™. According to Omdia, Hisense ranked No. 2 globally for TV shipments and No. 1 in 100″ TVs in both 2023 and Q1 2024. The company has expanded quickly to operate in more than 160 countries and specializes in multi-media goods, home appliances, and intelligent IT information.
View original content:https://www.prnewswire.co.uk/news-releases/experience-the-future-of-smart-living-with-hisense-at-ifa-2024-302241143.html
Artificial Intelligence
Changhong’s Innovative Technologies Take Center Stage at IFA 2024, Marking New Milestones in Global Growth
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BERLIN, Sept. 7, 2024 /PRNewswire/ — At IFA 2024, which opened on September 6, Changhong, a leading force in China’s home appliance industry, introduced its entire suite of AI-driven appliances. The presentation not only showcased Changhong’s recent achievements in AI technology but also marked a significant step toward expanding its influence in global markets.
Leading the charge in global innovation
On the event’s first day, Changhong unveiled its first Canghai Intelligent Agent AI TV, and the industry-leading Changhong AI Large Model specifically engineered for white goods.
The new AI TV can engage in voice conversations with users, think independently, and adapt through continuous learning. Utilizing its advanced technologies and complex multi-channel algorithms, Changhong has significantly improved the precision of voice recognition and activation.
The Changhong AI Large Model can be seamlessly embedded into household devices like refrigerators, washing machines, dryers, and air conditioners, enhancing accuracy and efficiency. For instance, it tailors refrigerator cooling to specific foods, adjusts washing machine and dryer settings by fabric types, and optimizes air conditioner settings for energy use and comfort. Through these integrations, Changhong elevates everyday interactions with home appliances.
Demonstrating brand strength with multiple awards
During the recent exhibition, the spotlight was on the Global Product Technology Innovation Awards where the Changhong CHiQ Xingbo Series clinched the Extraordinary Audio-Visual Experiences Gold Award. The recognition was for its superior technical performance, illustrating Changhong’s expertise in enhancing consumer experiences. Additionally, Changhong’s premium brand, CHiQ, was honored with the Smart Home Appliance Brand Award.
The event also saw CHiQ receiving the Organizational Greenhouse Gas Verification Statement from TÜV SÜD, along with the Product Carbon Footprint Verification Statement for CHiQ’s refrigerators and washing machines. These accolades highlight Changhong’s commitment to eco-friendly practices, pioneering sustainable household applications, and a robust green industrial chain.
Exemplifying international vision through sports marketing
During the event, CHiQ marked a significant moment in sports marketing with a signing ceremony for skiing projects. The brand announced its continued partnership with the FIS World Cup Events and the German Ski Association. Adding to the excitement, two-time Olympic skiing champion Andreas Wellinger was named the brand’s new ambassador, opening a new chapter in CHiQ’s marketing efforts.
James Wu, General Manager of Changhong International Brand Business Center, highlighted that renewing these projects is crucial for global expansion. The brand aims to strengthen its presence in Europe and key markets, leveraging collaborations to enhance CHiQ’s appeal and promote skiing worldwide.
Accelerating performance milestones to strengthen global footprint
Amid global market challenges, Changhong has shown resilience by integrating AI with consumer aspirations, offering innovative, advanced, and functional products. From January to July 2024, Changhong’s overseas home appliance revenue surged over 23% year-on-year, achieving performance milestones in TV, refrigerators, washing machines, and air conditioning lines.
In recent years, Changhong has accelerated its global expansion, focusing on delivering superior products and services. Committed to innovation, sustainability, and inclusiveness, the company plans to intensify R&D investments to realize an intelligent lifestyle for every household.
View original content:https://www.prnewswire.co.uk/news-releases/changhongs-innovative-technologies-take-center-stage-at-ifa-2024-marking-new-milestones-in-global-growth-302241138.html
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